Publication Name	World Journal of Stem Cells
Manuscript ID	39832
Country	Italy

Received	2018-05-23 01:01
Peer-Review Started	2018-05-25 00:09
To Make the First Decision	2018-06-06 07:40
Return for Revision	2018-06-08 01:31
Revised	2018-06-11 14:59
Second Decision	2018-06-27 08:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-28 16:41
Articles in Press	2018-06-28 16:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-18 00:14
Publish the Manuscript Online	2018-07-26 11:35

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Editorial
Article Title	Ectopic expression of the osteogenic master gene RUNX2 in melanoma
Manuscript Source	Invited Manuscript
All Author List	Maria Teresa Valenti, Luca Dalle Carbonare and Monica Mottes
ORCID	Author(s) ORCID Number Maria Teresa Valenti http://orcid.org/0000-0003-1166-8033 Luca Dalle Carbonare http://orcid.org/0000-0003-3263-6671 Monica Mottes http://orcid.org/0000-0002-7390-2246
Funding Agency and Grant Number
Corresponding Author	Maria Teresa Valenti, BSc, PhD, Chief Technician, Research Fellow, Department of Medicine, University of Verona, Ple Scuro 10, Verona 37100, Italy. mariateresa.valenti@univr.it
Key Words	RUNX2; Mesenchymal stem cells; Epitelial mesenchymal transition; Bone; Melanoma
Core Tip	In addition to its physiological expression in osteogenic cells, RUNX2 ectopic expression is also re­ported in several cancers. Melanoma cells, which arise from the neural crest, are not typical epithelial cells and exhibit “stemness” features. For this reason the epithelial mesenchymal transition process may be enhanced in melanoma cells. RUNX2 expression in such context in­creases the migration and invasiveness of melanoma cells; it can therefore be considered a new oncotarget in melanoma.
Publish Date	2018-07-26 11:35
Citation	Valenti MT, Dalle Carbonare L, Mottes M. Ectopic expression of the osteogenic master gene RUNX2 in melanoma. World J Stem Cells 2018; 10(7): 78-81
URL	http://www.wjgnet.com/1948-0210/full/v10/i7/78.htm
DOI	http://dx.doi.org/10.4252/wjsc.v10.i7.78

Full Article (PDF)	WJSC-10-78.pdf
Full Article (Word)	WJSC-10-78.doc
Manuscript File	39832-Review.docx
Answering Reviewers	39832-Answering reviewers.pdf
Audio Core Tip	39832-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	39832-Conflict-of-interest statement.pdf
Copyright License Agreement	39832-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	39832-Language certificate.pdf
Peer-review Report	39832-Peer-review(s).pdf
Scientific Misconduct Check	39832-Scientific misconduct check.pdf
Scientific Editor Work List	39832-Scientific editor work list.pdf