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Articles Published Processes
2/27/2020 7:38:25 AM | Browse: 639 | Download: 910
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Received |
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2019-09-11 11:21 |
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Peer-Review Started |
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2019-09-11 11:21 |
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To Make the First Decision |
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2019-11-04 00:37 |
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Return for Revision |
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2019-11-05 00:32 |
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Revised |
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2019-12-04 17:55 |
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Second Decision |
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2019-12-13 12:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-12-15 04:54 |
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Articles in Press |
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2019-12-15 04:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-01-08 03:29 |
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Publish the Manuscript Online |
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2020-02-27 07:38 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mazen Noureddin, Suntje Sander-Struckmeier and José M Mato |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
José M Mato, PhD, Director, Professor, CIBERehd, CIC BioGUNE, Parque Tecnológico de Bizkaia, Derio 48160, Bizkaia, Spain. director@cicbiogune.es |
| Key Words |
S-adenosylmethionine; Intrahepatic cholestasis; Chronic liver disease; Liver enzymes; Symptoms of cholestasis; |
| Core Tip |
Chronic liver diseases are associated with substantial mortality and morbidity, and are a significant healthcare burden. Therapies that rapidly reverse or inhibit the deterioration of liver function in patients with intrahepatic cholestasis would therefore be beneficial. In this study, we provide new insight into the efficacy of S-adenosylmethionine in treating these patients, demonstrating that S-adenosylmethionine improves some biochemical liver parameters and symptoms of cholestasis within 2 wk, with further improvements observed in some studies after 4 and 8 wk of treatment. |
| Publish Date |
2020-02-27 07:38 |
| Citation |
Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol 2020; 12(2): 46-63 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i2/46.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i2.46 |
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