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4/30/2020 3:27:13 PM | Browse: 731 | Download: 1091
Publication Name World Journal of Clinical Cases
Manuscript ID 55312
Country China
Received
2020-03-11 15:13
Peer-Review Started
2020-03-11 15:14
To Make the First Decision
Return for Revision
2020-04-01 05:10
Revised
2020-04-09 13:44
Second Decision
2020-04-16 08:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-04-16 22:44
Articles in Press
2020-04-16 22:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-04-20 03:47
Typeset the Manuscript
2020-04-28 01:11
Publish the Manuscript Online
2020-04-30 15:27
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Case Report
Article Title COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Mian Peng, Di Ren, Xue-Yan Liu, Jin-Xiu Li, Rong-Lin Chen, Bao-Jun Yu, Yong-Feng Liu, Xi Meng and Yan-Si Lyu
ORCID
Author(s) ORCID Number
Mian Peng http://orcid.org/0000-0001-5403-5565
Di Ren http://orcid.org/0000-0002-8422-2123
Xue-Yan Liu http://orcid.org/0000-0003-3604-4550
Jin-Xiu Li http://orcid.org/0000-0002-5959-2042
Rong-Lin Chen http://orcid.org/0000-0003-3124-3091
Bao-Jun Yu http://orcid.org/0000-0003-0883-9436
Yong-Feng Liu http://orcid.org/0000-0001-7426-1631
Xi Meng http://orcid.org/0000-0002-5170-2331
Yan-Si Lyu http://orcid.org/0000-0001-7909-9290
Funding Agency and Grant Number
Corresponding Author Xue-Yan Liu, PhD, Professor, Department of Intensive Care Unit, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, The Second Affiliated Hospital of Jinan University, Dongmen North Road No.1017, Luohu District, Shenzhen 518020, Guangdong Province, China. liuxueyan100916@163.com
Key Words COVID-19; Non-invasive ventilation; Bundle pharmacotherapy; Case report; Pneumonia; Coronavirus
Core Tip The coronavirus disease 2019 (COVID-19) outbreak has caused great panic and serious concern worldwide. Establishing effective control measures is of urgent importance. Here, we report the case of severe COVID-19, treated successfully with early non-invasive ventilation when the patient’s arterial oxygen partial pressure/fractional inspired oxygen ratio dropped below 200 mmHg, and bundle pharmacotherapy which included an antiviral cocktail (lopinavir/ritonavir plus γ-interferon), an immunity enhancer (thymosin), a corticosteroid to reduce pulmonary exudation (methylprednisolone), a traditional Chinese medicine-derived anti-inflammatory (Xuebijing), and an anti-coagulant to prevent deep vein thrombosis (heparin). The regimen of early non-invasive ventilation with bundle pharmacotherapy may be effective for patients with COVID-19.
Publish Date 2020-04-30 15:27
Citation Peng M, Ren D, Liu XY, Li JX, Chen RL, Yu BJ, Liu YF, Meng X, Lyu YS. COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report. World J Clin Cases 2020; 8(9): 1705-1712
URL https://www.wjgnet.com/2307-8960/full/v8/i9/1705.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i9.1705
Full Article (PDF) WJCC-8-1705.pdf
Full Article (Word) WJCC-8-1705.docx
CARE Checklist–2016 55312-CARE-Checklist–2016-revision.pdf
Manuscript File 55312-Review-Ma JY.docx
Answering Reviewers 55312-Answering reviewers.pdf
Audio Core Tip 55312-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 55312-Conflict-of-interest statement.pdf
Copyright License Agreement 55312-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 55312-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 55312-Language certificate.pdf
Peer-review Report 55312-Peer-review(s).pdf
Scientific Misconduct Check 55312-Scientific misconduct check.pdf
Scientific Editor Work List 55312-Scientific editor work list.pdf