| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shi-Wen Mei, Zheng Liu, Fang-Ze Wei, Jia-Nan Chen, Zhi-Jie Wang, Hai-Yu Shen, Juan Li, Fu-Qiang Zhao, Wei Pei, Zheng Wang, Xi-Shan Wang and Qian Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences |
2017-12M-1-006 |
| National Key Research and Development Plan "Research on Prevention and Control of Major Chronic Non-Communicable Diseases" |
2019YFC1315705 |
|
| Corresponding Author |
Qian Liu, MD, Chief Doctor, Professor, Surgeon, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com |
| Key Words |
Interval time; Advanced rectal cancer; Disease-free survival; Pathologic complete response; Neoadjuvant therapy; Surgery |
| Core Tip |
The time interval between neoadjuvant therapy and surgery is an underlying debate. This study mainly analyzed the effect of prolonging the time interval to surgery after neoadjuvant therapy on pathologic response and disease-free survival. Our study concluded that time interval > 9 wk will result in better prognosis and oncologic outcomes than time interval ≤ 9 wk. In practice, we should prolong the time interval to obtain favorable outcomes in advanced rectal cancer after neoadjuvant therapy. |
| Publish Date |
2020-08-21 06:42 |
| Citation |
Mei SW, Liu Z, Wei FZ, Chen JN, Wang ZJ, Shen HY, Li J, Zhao FQ, Pei W, Wang Z, Wang XS, Liu Q. Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients. World J Gastroenterol 2020; 26(31): 4624-4638 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i31/4624.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i31.4624 |
