| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Observational Study |
| Article Title |
Blood exosomal micro ribonucleic acid profiling reveals the complexity of hepatocellular carcinoma and identifies potential biomarkers for differential diagnosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lang-Qing Sheng, Jia-Rong Li, Hao Qin, Ling Liu, Da-Dong Zhang, Qi Zhang, Meng-Li Huang, Xiao-Li Li, Xiao-Ya Xu, Yang-Nian Wei, Zi-Shuo Chen, Hui Luo, Ji-Yang Zhang, Cheng-Hui Zhou, Hao Chen, Ze-Guo Chen, Fu-Gen Li and Nian-Feng Li |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Nian-Feng Li, MD, N/A, Department of Hepatobiliary and Pancreatic Surgery, Xiangya Hospital of Central South University, No.87 Xiangya road, Changsha 410008, Hunan Province, China. 1535909540@qq.com |
| Key Words |
Blood exosomal micro ribonucleic acids; Biomarker; Differential diagnosis; Alcohol consumption habit; Hepatocellular carcinoma; Bioinformatics |
| Core Tip |
To identify the potential biomarkers for Hepatocellular carcinoma (HCC) diagnosis, we focused on exosomal micro ribonucleic acids (miRNAs) using miRNA sequencing. To our knowledge, this is the first time to explore the exosomal miRNAs for differential diagnosis of HCC using miRNA sequencing. This study provided a hint to blood exosomal miRNAs can be used as new non-invasive diagnostic tools for HCC in clinical implementation. |
| Publish Date |
2020-10-14 13:53 |
| Citation |
Sheng LQ, Li JR, Qin H, Liu L, Zhang DD, Zhang Q, Huang ML, Li XL, Xu XY, Wei YN, Chen ZS, Luo H, Zhang JY, Zhou CH, Chen H, Chen ZG, Li FG, Li NF. Blood exosomal micro ribonucleic acid profiling reveals the complexity of hepatocellular carcinoma and identifies potential biomarkers for differential diagnosis.World J Gastrointest Oncol 2020; 12(10): 1195-1208 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i10/1195.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i10.1195 |
