Publication Name	World Journal of Gastroenterology
Manuscript ID	5771
Country	United States

Received	2013-09-25 21:11
Peer-Review Started	2013-09-26 18:09
To Make the First Decision	2013-10-14 21:12
Return for Revision	2013-10-16 13:49
Revised	2013-10-24 02:51
Second Decision	2013-11-13 11:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-13 15:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-21 16:03
Publish the Manuscript Online	2014-05-07 10:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Histological healing favors lower risk of colon carcinoma in extensive ulcerative colitis
Manuscript Source	Invited Manuscript
All Author List	Burton I Korelitz, Keith Sultan, Megha Kothari, Leo Arapos, Judy Schneider and Georgia Panagopoulos
Funding Agency and Grant Number	Funding Agency Grant Number New York Crohn’s Foundation
Corresponding Author	Burton I Korelitz, MD, Chief Emeritus, Director of Research in IBD, Department of Gastroenterology, Lenox Hill Hospital, 100 East 77th Street, 6 Black Hall, New York, NY 10075, United States. bkorelitz@nshs.edu
Key Words	Histological inflammation; Risk; Colon cancer; Ulcerative colitis; High grade dysplasia
Core Tip	Patients with long standing and extensive ulcerative colitis who develop colon cancer rarely have histological healing despite gross endoscopic healing. The persistence of histological inflammation is common in those who develop colon cancer (CC) or high grade dysplasia (HGD). When surveillance colonoscopies in ulcerative colitis of 20 years duration reveal persistent histological inflammation, patients are at high risk for the development of CC/HGD. Consideration of increasing drug therapy should arise, and the patient is entitled to share in this knowledge and contribute to the decision.
Publish Date	2014-05-07 10:10
Citation	Korelitz BI, Sultan K, Kothari M, Arapos L, Schneider J, Panagopoulos G. Histological healing favors lower risk of colon carcinoma in extensive ulcerative colitis. World J Gastroenterol 2014; 20(17): 4980-4986
URL	http://www.wjgnet.com/1007-9327/full/v20/i17/4980.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i17.4980

Full Article (PDF)	WJG-20-4980.pdf
Full Article (Word)	WJG-20-4980.doc
Manuscript File	5771-Review.docx
Answering Reviewers	5771-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20130925025629.docx
Copyright License Agreement	5771-Copyright assignment.pdf
Peer-review Report	5771-Peer reviews.pdf
Scientific Editor Work List	5771-Scientific editor work list.doc