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12/4/2020 9:56:59 AM | Browse: 741 | Download: 1262
Publication Name World Journal of Clinical Cases
Manuscript ID 59174
Country China
Received
2020-08-28 18:31
Peer-Review Started
2020-08-28 18:31
To Make the First Decision
Return for Revision
2020-09-29 18:25
Revised
2020-10-03 12:44
Second Decision
2020-10-19 08:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-20 03:11
Articles in Press
2020-10-20 03:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-11-02 00:33
Typeset the Manuscript
2020-12-01 07:49
Publish the Manuscript Online
2020-12-04 09:56
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Retrospective Study
Article Title Effect of methylprednisolone in severe and critical COVID-19: Analysis of 102 cases
Manuscript Source Invited Manuscript
All Author List Hong-Ming Zhu, Yan Li, Bang-Yi Li, Shuang Yang, Ding Peng, Xiaojiao Yang, Xue-Lian Sun and Mei Zhang
ORCID
Author(s) ORCID Number
Hong-Ming Zhu http://orcid.org/0000-0002-8596-177X
Yan Li http://orcid.org/0000-0002-2340-1937
Bang-Yi Li http://orcid.org/0000-0002-5944-9641
Shuang Yang http://orcid.org/0000-0003-0652-9266
Ding Peng http://orcid.org/0000-0003-3614-5538
Xiaojiao Yang http://orcid.org/0000-0003-3667-1239
Xue-Lian Sun http://orcid.org/0000-0003-3372-0410
Mei Zhang http://orcid.org/0000-0002-8596-1868
Funding Agency and Grant Number
Corresponding Author Mei Zhang, MD, Chief Physician, Occupational Physician, Professor, Department of Gastroenterology, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. zhang2955@sina.com
Key Words COVID-19; Glucocorticoids; Methylprednisolone; Cytokine storm; Coronavirus infections; Cytokines
Core Tip Glucocorticoids were used in the treatment of severe acute respiratory syndrome, influenza A and coronavirus disease 2019 (COVID-19) in the past. Many studies believe that glucocorticoids can effectively reduce inflammation caused by viruses. In this manuscript, 102 patients with severe and critical COVID-19 were studied and divided into treatment group and control group according to methylprednisolone use. We found that the difference in mortality between both groups was insignificant (P = 0.655), and the results showed that methylprednisolone treatment did not improve prognosis.
Publish Date 2020-12-04 09:56
Citation Zhu HM, Li Y, Li BY, Yang S, Peng D, Yang X, Sun XL, Zhang M. Effect of methylprednisolone in severe and critical COVID-19: Analysis of 102 cases. World J Clin Cases 2020; 8(23): 5952-5961
URL https://www.wjgnet.com/2307-8960/full/v8/i23/5952.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i23.5952
Full Article (PDF) WJCC-8-5952.pdf
Full Article (Word) WJCC-8-5952.docx
Manuscript File 59174_Auto_Edited_WangTQ.docx
Answering Reviewers 59174-Answering reviewers.pdf
Audio Core Tip 59174-Audio core tip.m4a
Biostatistics Review Certificate 59174-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 59174-Conflict-of-interest statement.pdf
Copyright License Agreement 59174-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 59174-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 59174-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 59174-Language certificate.pdf
Peer-review Report 59174-Peer-review(s).pdf
Scientific Misconduct Check 59174-Scientific editor work list.pdf
Scientific Misconduct Check 59174-Scientific misconduct check.pdf