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8/14/2021 11:08:14 AM | Browse: 378 | Download: 781
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 59880
Country South Korea
Received
2021-02-24 17:54
Peer-Review Started
2021-02-24 18:04
To Make the First Decision
Return for Revision
2021-04-19 04:50
Revised
2021-05-03 15:41
Second Decision
2021-07-09 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-09 12:04
Articles in Press
2021-07-09 12:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-08-09 02:01
Publish the Manuscript Online
2021-08-14 11:08
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy
Manuscript Source Unsolicited Manuscript
All Author List Kabsoo Shin, Eun-Kyo Jung, Se Jun Park, Sangwoon Jeong, In-Ho Kim and Myung-ah Lee
ORCID
Author(s) ORCID Number
Kabsoo Shin http://orcid.org/0000-0002-6709-0894
Eun-Kyo Jung http://orcid.org/0000-0002-6694-5723
Se Jun Park http://orcid.org/0000-0001-5486-9818
Sangwoon Jeong http://orcid.org/0000-0003-1780-6740
In-Ho Kim http://orcid.org/0000-0002-0351-2074
Myung-ah Lee http://orcid.org/0000-0002-1204-0574
Funding Agency and Grant Number
Corresponding Author Myung-ah Lee, MD, PhD, Professor, Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Secho-gu, Seoul 06591, South Korea. angelamd@catholic.ac.kr
Key Words Pancreatic adenocarcinoma; Serum carbohydrate antigen 19-9; Neutrophil-to-lymphocyte ratio; Multivariate analysis; Prognosis; Chemotherapy
Core Tip In pancreatic cancer patients treated with first-line chemotherapy, carbohydrate antigen 19-9 (CA19-9) decline is considered as a prognostic marker. However, there has been no consensus regarding the degree of CA19-9 decline, and certain populations show false negativity. We evaluated the cut-off value of decline of CA19-9 and post-treatment neutrophil-to-lymphocyte ratio (NLR) as prognostic makers. Combination of post-treatment NLR (< 2.62) and decline of CA19-9 (≥ 18%) for CA19-9 positive group or post-treatment NLR alone for CA19-9 negative group could be used as a prognostic marker and an adjuvant tool for response evaluation.
Publish Date 2021-08-14 11:08
Citation Shin K, Jung EK, Park SJ, Jeong S, Kim IH, Lee MA. Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy. World J Gastrointest Oncol 2021; 13(8): 915-928
URL https://www.wjgnet.com/1948-5204/full/v13/i8/915.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i8.915
Full Article (PDF) WJGO-13-915.pdf
Full Article (Word) WJGO-13-915.docx
Manuscript File 59880_Auto_Edited-ZMG.docx
Answering Reviewers 59880-Answering reviewers.pdf
Audio Core Tip 59880-Audio core tip.m4a
Biostatistics Review Certificate 59880-Biostatistics statement.PDF
Conflict-of-Interest Disclosure Form 59880-Conflict-of-interest statement.pdf
Copyright License Agreement 59880-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 59880-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 59880-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 59880-Language certificate.pdf
Supplementary Material 59880-Supplementary material.pdf
Peer-review Report 59880-Peer-review(s).pdf
Scientific Misconduct Check 59880-Bing-Wang JL-1.jpg
Scientific Misconduct Check 59880-Scientific misconduct check.pdf
Scientific Editor Work List 59880-Scientific editor work list.pdf