Publication Name	World Journal of Gastroenterology
Manuscript ID	6413
Country	Austria

Received	2013-10-17 15:08
Peer-Review Started	2013-10-18 14:27
To Make the First Decision	2013-12-03 18:58
Return for Revision	2013-12-05 11:25
Revised	2013-12-18 15:01
Second Decision	2014-01-20 17:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-20 18:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-14 13:45
Publish the Manuscript Online	2014-03-06 14:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Is the type of insufflation a key issue in gastro-intestinal endoscopy?
Manuscript Source	Invited Manuscript
All Author List	Amy C Lord and Stefan Riss
Funding Agency and Grant Number
Corresponding Author	Stefan Riss, MD, PD, FRCS, Department of General Surgery, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. stefan.riss@meduniwien.ac.at
Key Words	Gastrointestinal endoscopy; Colonoscopy; Endoscopic retrograde cholangiopancreatography; Insufflation gas; Carbon dioxide
Core Tip	With the increasing use of gastrointestinal endoscopy, especially for screening in an asymptomatic population, increasing the tolerability of the procedure is of paramount importance. Our review summarizes evidence that carbon dioxide (CO2) insufflation can reduce both pain and bloating in colonoscopy and endoscopic retrograde cholangiopancreatography although the evidence in gastroscopy is still lacking. Despite established safety concerns about hypercapnia, significant harm has never been demonstrated in the literature. Patients thought to be at higher risk of hypercapnia need to be included in more studies to demonstrate that CO2 insufflation is safe in an unselected screening population but early evidence is encouraging.
Publish Date	2014-03-06 14:13
Citation	Lord AC, Riss S. Is the type of insufflation a key issue in gastro-intestinal endoscopy? World J Gastroenterol 2014; 20(9): 2193-2199
URL	http://www.wjgnet.com/1007-9327/full/v20/i9/2193.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i9.2193

Full Article (PDF)	WJG-20-2193.pdf
Full Article (Word)	WJG-20-2193.doc
Manuscript File	6413-Review.docx
Answering Reviewers	6413-Answering reviewers.pdf
Copyright License Agreement	6413-Copyright assignment.pdf
Peer-review Report	6413-Peer review(s).pdf
Scientific Editor Work List	6413-Scientific editor work list.doc