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10/29/2021 12:16:53 PM | Browse: 356 | Download: 568
Publication Name World Journal of Clinical Cases
Manuscript ID 66549
Country United Kingdom
Received
2021-04-01 14:38
Peer-Review Started
2021-04-01 14:42
To Make the First Decision
Return for Revision
2021-06-24 10:33
Revised
2021-07-03 18:04
Second Decision
2021-09-17 03:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-19 08:43
Articles in Press
2021-09-19 08:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-25 01:41
Publish the Manuscript Online
2021-10-29 12:16
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Associations with pancreatic exocrine insufficiency: An United Kingdom single-centre study
Manuscript Source Invited Manuscript
All Author List Benjamin M Shandro, Joshua Chen, Jennifer Ritehnia and Andrew Poullis
ORCID
Author(s) ORCID Number
Benjamin M Shandro http://orcid.org/0000-0003-2496-5301
Joshua Chen http://orcid.org/0000-0003-4952-0296
Jennifer Ritehnia http://orcid.org/0000-0001-5885-3936
Andrew Poullis http://orcid.org/0000-0003-0703-0328
Funding Agency and Grant Number
Corresponding Author Benjamin M Shandro, MBBS, MRCP, Research Fellow, Department of Gastroenterology, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London SW17 0QT, United Kingdom. bshandro@nhs.net
Key Words Exocrine pancreatic insufficiency; Chronic pancreatitis; Pancreatic elastase; Steatorrhoea; Proton pump inhibitors
Core Tip Pancreatic exocrine insufficiency (PEI) is associated with chronic pancreatitis, pancreatic cancer, previous upper gastrointestinal surgery and type 2 diabetes. There should be a low threshold for testing for PEI in these patients. Proton pump inhibitor therapy may also be associated with PEI, or a false positive faecal elastase-1 (FE1). Until further evidence becomes available, we recommend repeat testing after a washout period. Steatorrhoea and weight loss were the only symptoms that predicted PEI in our cohort. Therefore, the diagnostic yield of FE1 testing in patients with non-specific presentations, such as bloating, is likely to be low.
Publish Date 2021-10-29 12:16
Citation Shandro BM, Chen J, Ritehnia J, Poullis A. Associations with pancreatic exocrine insufficiency: An United Kingdom single-centre study. World J Clin Cases 2021; 9(31): 9469-9480
URL https://www.wjgnet.com/2307-8960/full/v9/i31/9469.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i31.9469
Full Article (PDF) WJCC-9-9469.pdf
Full Article (Word) WJCC-9-9469.docx
Manuscript File 66549_Auto_Edited.docx
Answering Reviewers 66549-Answering reviewers.pdf
Audio Core Tip 66549-Audio core tip.m4a
Biostatistics Review Certificate 66549-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 66549-Conflict-of-interest statement.pdf
Copyright License Agreement 66549-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 66549-Institutional review board statement.pdf
Supplementary Material 66549-Supplementary material.pdf
Peer-review Report 66549-Peer-review(s).pdf
Scientific Misconduct Check 66549-Bing-Fan JR-2.png
Scientific Editor Work List 66549-Scientific editor work list.pdf