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9/17/2021 8:43:53 AM | Browse: 317 | Download: 594
Publication Name World Journal of Clinical Oncology
Manuscript ID 67832
Country Greece
Received
2021-05-03 13:45
Peer-Review Started
2021-05-03 13:47
To Make the First Decision
Return for Revision
2021-06-16 04:35
Revised
2021-06-19 12:06
Second Decision
2021-07-30 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-30 08:06
Articles in Press
2021-07-30 08:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-08-09 21:18
Typeset the Manuscript
2021-09-16 05:17
Publish the Manuscript Online
2021-09-17 08:43
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Hematopoietic stem cell mobilization strategies to support high-dose chemotherapy: A focus in relapsed/refractory germ-cell tumors
Manuscript Source Invited Manuscript
All Author List Eleni Porfyriou, Sylvia Letsa and Christos Kosmas
ORCID
Author(s) ORCID Number
Eleni Porfyriou http://orcid.org/0000-0003-0667-6952
Sylvia Letsa http://orcid.org/0000-0001-5418-7219
Christos Kosmas http://orcid.org/0000-0001-6790-5785
Funding Agency and Grant Number
Corresponding Author Eleni Porfyriou, MD, Doctor, Department of Medical Oncology and Hematopoietic Cell Transplant Unit, “Metaxa” Cancer Hospital, 51 Botassi Street, Piraeus 18537, Greece. porfyriou7@gmail.com
Key Words Hematopoietic stem cells; Germ-cell tumors; Hematopoietic stem cell transplantation; Granulocyte-colony-stimulating factor; Plerixafor
Core Tip High-dose chemotherapy (HDCT) followed by autologous stem cell transplantation (ASCT) represents a curative treatment option for patients with relapsed/refractory germ-cell tumors (GCTs). Mobilization of adequate numbers of hematopoietic stem cells (HSCs) is a prerequisite for successful ASCT. As the benefit of HDCT+ASCT is largely evident with > one HDCT cycle, it is anticipated that an appreciable percentage of patients will not mobilize adequate HSCs and require salvage strategies. Herein, we review the history of HSC transplantation, with emphasis in GCTs, pathophysiological mechanisms of HSC mobilization, initial and salvage mobilization strategies, and finally discuss novel mobilizing agents and approaches to overcome failures.
Publish Date 2021-09-17 08:43
Citation Porfyriou E, Letsa S, Kosmas C. Hematopoietic stem cell mobilization strategies to support high-dose chemotherapy: A focus in relapsed/refractory germ cell tumors. World J Clin Oncol 2021; 12(9): 746-766
URL https://www.wjgnet.com/2218-4333/full/v12/i9/746.htm
DOI https://dx.doi.org/10.5306/wjco.v12.i9.746
Full Article (PDF) WJCO-12-746.pdf
Full Article (Word) WJCO-12-746.docx
Manuscript File 67832-Review-FilipodiaCL.docx
Answering Reviewers 67832-Answering reviewers.pdf
Audio Core Tip 67832-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 67832-Conflict-of-interest statement.pdf
Copyright License Agreement 67832-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 67832-Language certificate.pdf
Peer-review Report 67832-Peer-review(s).pdf
Scientific Misconduct Check 67832-CrossCheck.png
Scientific Misconduct Check 67832-Bing-Gong ZM-2.png
Scientific Misconduct Check 67832-Scientific misconduct check.pdf
Scientific Editor Work List 67832-Scientific editor work list.pdf