Publication Name	World Journal of Clinical Cases
Manuscript ID	68395
Country	China

Received	2021-05-21 15:34
Peer-Review Started	2021-05-21 15:37
To Make the First Decision
Return for Revision	2021-06-15 02:33
Revised	2021-06-28 17:26
Second Decision	2021-08-20 02:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-08-20 03:08
Articles in Press	2021-08-20 03:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-05 09:32
Typeset the Manuscript	2021-10-17 15:21
Publish the Manuscript Online	2021-10-21 08:44

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Diagnosis and treatment analysis of primary pulmonary enteric adenocarcinoma: Six case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Ling-Fang Tu, Ling-Yan Sheng, Jian-Ying Zhou, Xue-Fen Wang, Yue-Hong Wang, Qian Shen and Yi-Hong Shen
ORCID	Author(s) ORCID Number Ling-Fang Tu http://orcid.org/0000-0003-4348-6592 Ling-Yan Sheng http://orcid.org/0000-0003-2491-3675 Jian-Ying Zhou http://orcid.org/0000-0002-8924-935X Xue-Fen Wang http://orcid.org/0000-0002-3953-7388 Yue-Hong Wang http://orcid.org/0000-0002-0719-3197 Qian Shen http://orcid.org/0000-0001-5820-6034 Yi-Hong Shen http://orcid.org/0000-0002-7815-9973
Funding Agency and Grant Number	Funding Agency Grant Number Medicine and Health Project of Zhejiang Province, China 2018KY049
Corresponding Author	Yi-Hong Shen, MD, Chief Doctor, Department of Respiratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. drsyh@zju.edu.cn
Key Words	Pulmonary enteric adenocarcinoma; Immunohistochemistry; Diagnosis; Treatment; KRAS; Case report
Core Tip	Primary pulmonary enteric adenocarcinoma (PEAC) is a very rare subtype of invasive adenocarcinoma, and there have been no large studies on PEAC to date. All clinical data of six patients with confirmed PEAC from 2013 to 2018 were collected in this study, and data on the diagnosis, differential diagnosis and treatment of PEAC were simultaneously discussed with all associated literature. Our findings highlight that positive results for CDX2 and CK7 play an important role in the diagnosis and differential diagnosis of PEAC, and immunotherapy or targeted therapy focused on KRAS needs to be further studied for the treatment of PEAC.
Publish Date	2021-10-21 08:44
Citation	Tu LF, Sheng LY, Zhou JY, Wang XF, Wang YH, Shen Q, Shen YH. Diagnosis and treatment analysis of primary pulmonary enteric adenocarcinoma: Six case reports. World J Clin Cases 2021; 9(30): 9236-9243
URL	https://www.wjgnet.com/2307-8960/full/v9/i30/9236.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i30.9236

Full Article (PDF)	WJCC-9-9236.pdf
Full Article (Word)	WJCC-9-9236.docx
CARE Checklist–2016	68395-CARE-Checklist–2016-revision.pdf
Manuscript File	68395_Auto_Edited-JPY_WangTQ.docx
Answering Reviewers	68395-Answering reviewers.pdf
Audio Core Tip	68395-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	68395-Conflict-of-interest statement.pdf
Copyright License Agreement	68395-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	68395-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	68395-Informed consent statement.pdf
Supplementary Material	68395-Supplementary material.pdf
Peer-review Report	68395-Peer-review(s).pdf
Scientific Misconduct Check	68395-Scientific misconduct check.pdf
Scientific Editor Work List	68395-Scientific editor work list.pdf