| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Diagnostic performance of Neutrophil CD64 index, procalcitonin, and C-reactive protein for early sepsis in hematological patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Xi Shang, Zhi Zheng, Min Wang, Hui-Xia Guo, Yi-Juan Chen, Yue Wu, Xing Li, Qian Li, Jian-Ying Cui, Xiao-Xiao Ren and Li-Ru Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Xicheng District Outstanding Talent Project |
2018-2019, Yuxi Shang |
| Beijing Xicheng District Health Commission Young Science and Technology Talent (Science and Technology New Star) Training Project |
xwkx2020-24 |
|
| Corresponding Author |
Li-Ru Wang, MD, PhD, Chief Doctor, Director, Doctor, Department of Hematology, Fuxing Hospital, Eighth Clinical Medical College, Capital Medical University, No.20, Fuxing street, Xicheng District, Beijing, China, Beijing 100038, China. liruwang@ccmu.edu.cn |
| Key Words |
CD64 index; Hematological diseases; Sepsis; Procalcitonin; C-reactive protein |
| Core Tip |
Early sepsis in hematological patients is difficult to diagnosis, often progresses rapidly, and has a high mortality rate. The neutrophil CD64 (nCD64) index has high sensitivity and specificity as a diagnostic marker of early sepsis. We confirm the usefulness of this index in hematological patients, with the diagnostic efficacy of the nCD64 index for early sepsis in this clinical population being significantly better than high-sensitivity C-reactive protein and superior to procalcitonin. The index can be helpful in evaluating the severity of infection in patients with hematological diseases. |
| Publish Date |
2022-03-02 04:52 |
| Citation |
Shang YX, Zheng Z, Wang M, Guo HX, Chen YJ, Wu Y, Li X, Li Q, Cui JY, Ren XX, Wang LR. Diagnostic performance of Neutrophil CD64 index, procalcitonin, and C-reactive protein for early sepsis in hematological patients. World J Clin Cases 2022; 10(7): 2127-2137 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i7/2127.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i7.2127 |
