Publication Name	World Journal of Clinical Cases
Manuscript ID	71179
Country	China

Received	2021-09-01 10:30
Peer-Review Started	2021-09-01 10:31
To Make the First Decision
Return for Revision	2021-11-22 07:49
Revised	2021-11-30 15:35
Second Decision	2022-03-02 06:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-06 21:59
Articles in Press	2022-03-06 21:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-11 00:29
Publish the Manuscript Online	2022-04-21 11:35

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Respiratory System
Manuscript Type	Case Report
Article Title	Cryptococcal antigen testing of lung tissue homogenate improves pulmonary cryptococcosis diagnosis: Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Wei-Yi Wang, Yu-Lu Zheng and Li-Bin Jiang
ORCID	Author(s) ORCID Number Wei-Yi Wang http://orcid.org/0000-0003-2563-6294 Yu-Lu Zheng http://orcid.org/0000-0003-1218-9480 Li-Bin Jiang http://orcid.org/0000-0002-4527-7770
Funding Agency and Grant Number
Corresponding Author	Li-Bin Jiang, Doctor, MD, Chief Doctor, Department of Respiratory Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Youdian Road No.54, Hangzhou 310006, Zhejiang Province, China. jkzjuedu@163.com
Key Words	Lung tissue homogenate; Cryptococcal antigen test; Pulmonary cryptococcosis; Lung biopsy; Diagnosis; Case report
Core Tip	Pulmonary cryptococcosis (PC) is often misdiagnosed or underdiagnosed owing to the absence of obvert symptoms, poor imaging specificity, and false-negative laboratory tests. We presented two cases of PC wherein serum cryptococcal antigen (CrAg) tests were negative; however, CrAg tests using lung tissue homogenate were positive. Our report aims to highlight the dilemma in diagnosing PC, as well as a novel adjunct in the diagnostic work-up for PC–cryptococcal antigen tests on lung tissue homogenates.
Publish Date	2022-04-21 11:35
Citation	Wang WY, Zheng YL, Jiang LB. Cryptococcal antigen testing of lung tissue homogenate improves pulmonary cryptococcosis diagnosis: Two case reports. World J Clin Cases 2022; 10(12): 3893-3898
URL	https://www.wjgnet.com/2307-8960/full/v10/i12/3893.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i12.3893

Full Article (PDF)	WJCC-10-3893.pdf
Full Article (Word)	WJCC-10-3893.docx
CARE Checklist–2016	71179-CARE-Checklist–2016-revision.pdf
Manuscript File	71179_Auto_Edited-LJH.docx
Answering Reviewers	71179-Answering reviewers.pdf
Audio Core Tip	71179-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	71179-Conflict-of-interest statement.pdf
Copyright License Agreement	71179-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	71179-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	71179-Language certificate.pdf
Peer-review Report	71179-Peer-review(s).pdf
Scientific Misconduct Check	71179-Bing-Liu JH-2.jpg
Scientific Misconduct Check	71179-CrossCheck.jpg
Scientific Editor Work List	71179-Scientific editor work list.pdf