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Articles Published Processes
2/11/2022 5:55:20 AM | Browse: 266 | Download: 403
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Received |
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2021-09-08 02:51 |
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Peer-Review Started |
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2021-09-08 02:52 |
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To Make the First Decision |
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Return for Revision |
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2021-10-27 00:15 |
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Revised |
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2021-11-26 05:49 |
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Second Decision |
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2022-01-07 05:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-01-08 02:15 |
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Articles in Press |
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2022-01-08 02:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-12-29 00:33 |
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Typeset the Manuscript |
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2022-01-24 10:43 |
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Publish the Manuscript Online |
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2022-02-11 05:55 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Case Report |
| Article Title |
Hepatitis B virus in cerebrospinal fluid of a patient with purulent bacterial meningitis detected by multiplex-PCR: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dai-Quan Gao, Yong-Qiang Hu, Xin Wang and Yun-Zhou Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yun-Zhou Zhang, PhD, Chief Physician, Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. bjyuz657@163.com |
| Key Words |
Purulent meningitis; Streptococcus pneumoniae; Hepatitis B virus; Multiplex PCR; Cerebrospinal fluid; Case report |
| Core Tip |
The advantages of multiplex PCR are rapid detection and high sensitivity and accuracy. Multiplex PCR can assist in the diagnosis of bacterial and viral meningitis in culture-negative cerebrospinal fluid (CSF). Furthermore, this technique can improve the accuracy of diagnosis of acute bacterial meningitis (BM) in the clinical setting in culture-positive or culture-negative CSF. We report a rare case of hepatitis B virus (HBV) in the CSF of a patient with purulent BM and demonstrate that multiplex PCR is more sensitive than metagenomic next-generation sequencing for detecting HBV DNA. |
| Publish Date |
2022-02-11 05:55 |
| Citation |
Gao DQ, Hu YQ, Wang X, Zhang YZ. Hepatitis B virus in cerebrospinal fluid of a patient with purulent bacterial meningitis detected by multiplex-PCR: A case report. World J Clin Cases 2022; 10(5): 1697-1701 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i5/1697.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i5.1697 |
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