ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Report |
Article Title |
Toripalimab combined with targeted therapy and chemotherapy perioperatively achieves pathologic complete response in gastric carcinoma: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Rui Liu, Xia Wang, Zhi Ji, Ting Deng, Hong-Li Li, Yan-Hui Zhang, Yu-Chong Yang, Shao-Hua Ge, Le Zhang, Ming Bai, Tao Ning and Yi Ba |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Chinese Research Hospital Association |
Y2019FH-DTCC-SC3 |
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Corresponding Author |
Rui Liu, Doctor, Chief Doctor, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, North Huanhu West Road, Sports Institute, Hexi District, Tianjin 300000, China. ruiliu688@126.com |
Key Words |
Toripalimab; Targeted therapy; Chemotherapy; Perioperative management; Gastric carcinoma; Case report |
Core Tip |
We report a case in which pathologic complete response was achieved by neoadjuvant administration of toripalimab, Herceptin, and docetaxel, oxaliplatin, calcium folinate, and fluorouracil chemotherapy followed by surgery for human epidermal growth factor receptor 2-positive and programmed death-ligand 1-positive locally advanced gastric carcinoma. We hope that this case will shed some light on neoadjuvant therapy for gastric carcinoma. |
Publish Date |
2022-06-17 03:19 |
Citation |
Liu R, Wang X, Ji Z, Deng T, Li HL, Zhang YH, Yang YC, Ge SH, Zhang L, Bai M, Ning T, Ba Y. Toripalimab combined with targeted therapy and chemotherapy achieves pathologic complete response in gastric carcinoma: A case report. World J Clin Cases 2022; 10(18): 6184-6191 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i18/6184.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i18.6184 |