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Articles Published Processes
7/27/2022 2:48:54 AM | Browse: 182 | Download: 361
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Received |
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2022-04-07 12:22 |
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Peer-Review Started |
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2022-04-07 12:24 |
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To Make the First Decision |
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Return for Revision |
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2022-05-09 06:12 |
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Revised |
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2022-05-21 08:57 |
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Second Decision |
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2022-06-29 03:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-06-30 22:27 |
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Articles in Press |
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2022-06-30 22:27 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-01 06:30 |
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Publish the Manuscript Online |
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2022-07-27 02:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Delayed immune-related sclerosing cholangitis after discontinuation of pembrolizumab: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Takeshi Tanaka, Arata Sakai, Masahiro Tsujimae, Yasutaka Yamada, Takashi Kobayashi, Atsuhiro Masuda and Yuzo Kodama |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| JSPS KAKENHI |
JP19K07938 |
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| Corresponding Author |
Arata Sakai, PhD, Doctor, Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Hyogo, Japan. asakai@med.kobe-u.ac.jp |
| Key Words |
Immune-related adverse events; Sclerosing cholangitis; Delayed immune-related events; Case report |
| Core Tip |
Immune checkpoint inhibitors have become a new standard in cancer treatment, but have often been reported to induce adverse events, called immune-related adverse events (irAEs). Biliary system complications, such as irAEs, remain rare, and the management strategy remains unclear. We present herein, a rare case of delayed immune-related sclerosing cholangitis (SC) after discontinuation of pembrolizumab. Our case emphasizes that immune-related SC can occur later, but the mechanisms have not yet been elucidated. As such, our case contributes to new knowledge in the hopes of being able to establish proper diagnostic criteria and management strategies for similar patients. |
| Publish Date |
2022-07-27 02:48 |
| Citation |
Tanaka T, Sakai A, Tsujimae M, Yamada Y, Kobayashi T, Masuda A, Kodama Y. Delayed immune-related sclerosing cholangitis after discontinuation of pembrolizumab: A case report. World J Gastroenterol 2022; 28(28): 3732-3738 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i28/3732.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i28.3732 |
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