Publication Name	World Journal of Gastroenterology
Manuscript ID	77618
Country	Spain

Received	2022-05-11 13:06
Peer-Review Started	2022-05-11 13:09
To Make the First Decision
Return for Revision	2022-06-27 23:21
Revised	2022-07-01 08:20
Second Decision	2022-08-30 03:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-31 20:02
Articles in Press	2022-08-31 20:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-08-25 13:44
Typeset the Manuscript	2022-09-02 02:02
Publish the Manuscript Online	2022-09-15 13:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Toxicology
Manuscript Type	Letter to the Editor
Article Title	Hepatitis B viral infection and role of alcohol
Manuscript Source	Unsolicited Manuscript
All Author List	Manuel Muro, Aurelia Collados-Ros and Isabel Legaz
ORCID	Author(s) ORCID Number Manuel Muro http://orcid.org/0000-0001-9987-0994 Isabel Legaz http://orcid.org/0000-0002-1140-4313
Funding Agency and Grant Number
Corresponding Author	Isabel Legaz, PhD, Senior Lecturer, Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence "Campus Mare Nostrum", Faculty of Medicine, University of Murcia (Spain), Universidad de Murcia, Campus de Espinardo, Facultad de Medicina, Espinardo 30100, Murcia, Spain. isalegaz@um.es
Key Words	Hepatitis B virus; Alcohol; Hepatocarcinoma; Immunity; Liver disease
Core Tip	In this letter to the editor, we comment on and discuss the combined effects of alcohol consumption and hepatitis B virus (HBV) infection in the progression of liver diseases. In the worst evolution of end-stage liver pathologies, a concordant clinical relationship between alcohol consumption and HBV infection starts to be revealed. There are many potential causes, but some might include increased viral replication, oxidative stress on cellular organelles, and weakened immune responses. Understanding these precepts will open new avenues in managing and treating these patients.
Publish Date	2022-09-15 13:37
Citation	Muro M, Collados-Ros A, Legaz I. Hepatitis B viral infection and role of alcohol. World J Gastroenterol 2022; 28(35): 5233-5236
URL	https://www.wjgnet.com/1007-9327/full/v28/i35/5233.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i35.5233

Full Article (PDF)	WJG-28-5233.pdf
Full Article (Word)	WJG-28-5233.docx
Manuscript File	77618_Auto_Edited-YLC-Wang TQ-LS.docx
Answering Reviewers	77618-Answering reviewers.pdf
Audio Core Tip	77618-Audio core tip.wav
Conflict-of-Interest Disclosure Form	77618-Conflict-of-interest statement.pdf
Copyright License Agreement	77618-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	77618-Language certificate.pdf
Peer-review Report	77618-Peer-review(s).pdf
Scientific Misconduct Check	77618-Bing-Chen YL-2.png
Scientific Editor Work List	77618-Scientific editor work list.pdf