| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinicopathological characteristics and prognosis of gastric signet ring cell carcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua-Kai Tian, Zuo Zhang, Zhi-Kun Ning, Jiang Liu, Zi-Tao Liu, Hao-Yu Huang, Zhen Zong and Hui Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangxi Provincial Education Department, Science and Technology Research Project-Youth Project |
GJJ210252 |
| Research Subject of Educational Reform of Nanchang University |
NCUJGLX-2022-160-96 |
|
| Corresponding Author |
Hui Li, MD, Doctor, Department of Rheumatology and Immunology, First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Donghu District, Nanchang 330006, Jiangxi Province, China. lihui0791nc@126.com |
| Key Words |
Gastric adenocarcinoma; Gastric signet ring cell carcinoma; Pathological features; Survival prognosis; Prognostic model; Adjuvant therapy |
| Core Tip |
This observational study analysed the clinicopathological features and prognosis of gastric signet ring cell carcinoma (GSRC). We compared GSRC with differentiated gastric adenocarcinoma and found that GSRC has unique clinicopathological features, is more common in younger female patients, and is more aggressive, showing higher lymph node metastasis and tumour size. However, the prognosis for early GSRC was relatively good, even higher than that of differentiated adenocarcinoma. The treatment of GSRC should be diagnosed early, and radical surgical resection with adjuvant radiotherapy and chemotherapy can significantly improve the survival rate of patients, though it still needs more clinical data to verify. |
| Publish Date |
2022-09-29 09:17 |
| Citation |
Tian HK, Zhang Z, Ning ZK, Liu J, Liu ZT, Huang HY, Zong Z, Li H. Clinicopathological characteristics and prognosis of gastric signet ring cell carcinoma. World J Clin Cases 2022; 10(29): 10451-10466 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i29/10451.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i29.10451 |
