| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Bariatric surgery on glucose and lipid metabolism, and liver and kidney functions in food-derived obese diabetic rats
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong Long, Lei Zhao, Zhong-Sheng Xiao, Shu-Xiang Li, Qiu-Lin Huang, Shuai Xiao and Liang-Liang Wu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Hunan Province |
2021JJ70119 |
|
| Corresponding Author |
Liang-Liang Wu, MM, Attending Doctor, Department of Gastrointestinal Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, No. 69 Chuanshan Road, Shigu District, Hengyang 421001, Hunan Province, China. 2018012015@usc.edu.cn |
| Key Words |
Diabetes mellitus; Obesity; Bariatric surgeries; Liver and kidney functions |
| Core Tip |
Bariatric surgery can improve the symptoms of type 2 diabetes mellitus (DM) in some obese patients. But different types of bariatric surgery may have different effects. In the current study, in comparison to the sham operation group, Roux-en-Y gastric bypass surgery (RYGB), sleeve gastrectomy (SG), and gastric banding (GB) groups had decreased body weight and food intake, reduced glucose intolerance and insulin insensitivity, downregulated biochemical parameters, alleviation of morphological changes in the liver and kidneys, and decreased levels of protein kinase C β/P66shc. The effect in the RYGB group was better than in the SG and GB groups. Here, we introduced bariatric surgeries as a helpful tool for the treatment of food-derived obese DM. |
| Publish Date |
2023-08-11 11:04 |
| Citation |
Long H, Zhao L, Xiao ZS, Li SX, Huang QL, Xiao S, Wu LL. Bariatric surgery on glucose and lipid metabolism, and liver and kidney functions in food-derived obese diabetic rats. World J Diabetes 2023; 14(8): 1249-1258 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i8/1249.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i8.1249 |
