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Articles Published Processes
11/24/2023 4:14:40 AM | Browse: 88 | Download: 126
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Received |
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2023-07-17 17:27 |
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Peer-Review Started |
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2023-07-17 17:29 |
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To Make the First Decision |
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Return for Revision |
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2023-08-22 22:58 |
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Revised |
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2023-09-14 16:00 |
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Second Decision |
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2023-10-27 02:00 |
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Accepted by Journal Editor-in-Chief |
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2023-10-29 10:41 |
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Accepted by Company Editor-in-Chief |
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2023-11-15 09:08 |
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Articles in Press |
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2023-11-15 09:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-10-26 20:55 |
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Typeset the Manuscript |
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2023-11-21 09:02 |
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Publish the Manuscript Online |
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2023-11-24 04:14 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Minireviews |
| Article Title |
How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qing-Xiang Zhang and Min Cui |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82202766 |
| Science Foundation of Union Hospital |
No. 2021xhyn102 |
| Scientific Research Training Program for Young Talents in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China. |
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| Natural Science Foundation of Hubei Province of China |
No. 2022CFB686 |
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| Corresponding Author |
Min Cui, MD, PhD, Associate Chief Physician, Associate Professor, Doctor, Department of Orthopedics,Union Hospital, Tongji Medical College,Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. cm95588@hust.edu.cn |
| Key Words |
Mesenchymal stem cells; Intervertebral disc degeneration; Extracellular vesicles; Nucleus pulposus cells; Tissue regeneration |
| Core Tip |
Mesenchymal stem cells have a strong self-renewal capacity and multidirectional differentiation potential, and their secreted vesicles promote regeneration of myeloid cells, increase extracellular matrix production, and alleviate inflammatory status. We reviewed the current relevant targets of stem cell exosomes for the treatment of intervertebral discs and the adjuvant tools used in conjunction with stem cell therapy. This will help to improve the therapeutic efficacy of stem cells and their exosomes, which will also contribute to development of more efficient treatment strategies and approaches for the restoration of disc degeneration. |
| Publish Date |
2023-11-24 04:14 |
| Citation |
Zhang QX, Cui M. How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration. World J Stem Cells 2023; 15(11): 989-998 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i11/989.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i11.989 |
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