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12/14/2023 9:36:12 AM | Browse: 81 | Download: 152
Publication Name World Journal of Diabetes
Manuscript ID 87685
Country China
Received
2023-08-22 08:50
Peer-Review Started
2023-08-22 08:52
To Make the First Decision
Return for Revision
2023-09-19 05:16
Revised
2023-09-28 12:11
Second Decision
2023-11-16 02:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-27 06:41
Articles in Press
2023-11-27 06:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-12-08 06:16
Publish the Manuscript Online
2023-12-14 09:36
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Basic Study
Article Title Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice
Manuscript Source Unsolicited Manuscript
All Author List Qi-Yan Sun, Xu-Ye Wang, Zu-Pin Huang, Jing Song, En-Dong Zheng, Fang-Hua Gong and Xiao-Wang Huang
ORCID
Author(s) ORCID Number
Qi-Yan Sun http://orcid.org/0000-0001-8573-5628
Fang-Hua Gong http://orcid.org/0000-0002-8905-4894
Xiao-Wang Huang http://orcid.org/0009-0006-2219-9091
Funding Agency and Grant Number
Funding Agency Grant Number
the 2022 Zhejiang Provincial Health Science and Technology Plan 2022KY1216
Corresponding Author Fang-Hua Gong, MD, Associate Professor, School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, Zhejiang Province, China. gongwenheng@163.com
Key Words Acute pancreatitis; Fibroblast growth factor 21; Gut microbiota; Diabetes; PICRUSt2; Cocktail of antibiotics
Core Tip This study reveals the potential of facilitates fibroblast growth factor 21 (FGF21) in improving pancreatic and intestinal damage recovery, reducing blood glucose levels, and reshaping gut microbiota composition in diabetic mice with acute pancreatitis (AP). Notably, the protective effects of FGF21 are augmented when combined with the Abx cocktail. These findings provide new insights into the prevention and treatment of diabetes complicated by AP.
Publish Date 2023-12-14 09:36
Citation Sun QY, Wang XY, Huang ZP, Song J, Zheng ED, Gong FH, Huang XW. Depletion of gut microbiota facilitates fibroblast growth factor 21-mediated protection against acute pancreatitis in diabetic mice. World J Diabetes 2023; 14(12): 1824-1838
URL https://www.wjgnet.com/1948-9358/full/v14/i12/1824.htm
DOI https://dx.doi.org/10.4239/wjd.v14.i12.1824
Full Article (PDF) WJD-14-1824-with-cover.pdf
Full Article (Word) WJD-14-1824.docx
The ARRIVE Guidelines 87685-The ARRIVE guidelines.pdf
Manuscript File 87685_Auto_Edited-LM.docx
Answering Reviewers 87685-Answering reviewers.pdf
Audio Core Tip 87685-Audio core tip.mp3
Biostatistics Review Certificate 87685-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 87685-Conflict-of-interest statement.pdf
Copyright License Agreement 87685-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 87685-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 87685-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 87685-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 87685-Language certificate.pdf
Peer-review Report 87685-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 87685-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 87685-Bing-Lin C-2.png
Scientific Editor Work List 87685-Scientific editor work list.pdf