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11/27/2023 5:08:21 PM | Browse: 106 | Download: 299
Publication Name World Journal of Gastroenterology
Manuscript ID 88755
Country China
Received
2023-10-08 02:53
Peer-Review Started
2023-10-08 02:55
To Make the First Decision
Return for Revision
2023-11-01 01:48
Revised
2023-11-06 13:02
Second Decision
2023-11-10 09:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-14 08:42
Articles in Press
2023-11-14 08:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-11-22 03:44
Publish the Manuscript Online
2023-11-27 17:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Clinical and Translational Research
Article Title Causal associations between inflammatory bowel disease and anxiety: A bidirectional Mendelian randomization study
Manuscript Source Unsolicited Manuscript
All Author List Ying He, Chun-Lan Chen, Jian He and Si-De Liu
ORCID
Author(s) ORCID Number
Ying He http://orcid.org/0000-0001-7295-0089
Chun-Lan Chen http://orcid.org/0000-0001-6878-8461
Jian He http://orcid.org/0000-0002-8644-2605
Si-De Liu http://orcid.org/0000-0001-8192-988X
Funding Agency and Grant Number
Funding Agency Grant Number
China Postdoctoral Science Foundation No. 2021M701614
Guangdong Basic and Applied Basic Research Foundation No. 2022A1515111063 and No. 2022A1515111045
Foundation of Guangdong Provincial People's Hospital No. 8200010545
Corresponding Author Si-De Liu, PhD, Professor, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou 510515, Guangdong Province, China. liuside2011@163.com
Key Words Inflammatory bowel disease; Anxiety; Causal effect; Mendelian randomization; Genome-wide association studies
Core Tip Our study provides evidence that genetic susceptibility to ulcerative colitis (UC) is associated with an increased risk of anxiety [odds ratio: 1.071 (95% confidence interval: 1.009, 1.135), P = 0.023], while genetic susceptibility to Crohn’s disease (CD) is not associated with an increased risk of anxiety. No causal effects of anxiety on UC and CD were observed in this study. In conclusion, our study demonstrates the causal effect of UC on anxiety. These findings may be helpful to increase physicians’ awareness of the need to recognize anxiety in UC patients and influence the management of anxiety in clinical practice.
Publish Date 2023-11-27 17:08
Citation He Y, Chen CL, He J, Liu SD. Causal associations between inflammatory bowel disease and anxiety: A bidirectional Mendelian randomization study. World J Gastroenterol 2023; 29(44): 5872-5881
URL https://www.wjgnet.com/1007-9327/full/v29/i44/5872.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i44.5872
Full Article (PDF) WJG-29-5872-with-cover.pdf
Full Article (Word) WJG-29-5872.docx
Manuscript File 88755_Auto_Edited-JLW.docx
Answering Reviewers 88755-Answering reviewers.pdf
Audio Core Tip 88755-Audio core tip.mp3
Biostatistics Review Certificate 88755-Biostatistics statement.pdf
Clinical Trial Registration Statement 88755-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 88755-Conflict-of-interest statement.pdf
Copyright License Agreement 88755-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 88755-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 88755-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 88755-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 88755-Language certificate.pdf
Supplementary Material 88755-Supplementary material.pdf
Peer-review Report 88755-Peer-review(s).pdf
Scientific Misconduct Check 88755-Bing-Qu XL-2.png
Scientific Editor Work List 88755-Scientific editor work list.pdf