| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Guidelines |
| Article Title |
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Faisal Saud Dar, Zaigham Abbas, Irfan Ahmed, Muhammad Atique, Usman Iqbal Aujla, Muhammad Azeemuddin, Zeba Aziz, Abu Bakar Hafeez Bhatti, Tariq Ali Bangash, Amna Subhan Butt, Osama Tariq Butt, Abdul Wahab Dogar, Javed Iqbal Farooqi, Faisal Hanif, Jahanzaib Haider, Siraj Haider, Syed Mujahid Hassan, Adnan Abdul Jabbar, Aman Nawaz Khan, Muhammad Shoaib Khan, Muhammad Yasir Khan, Amer Latif, Nasir Hassan Luck, Ahmed Karim Malik, Kamran Rashid, Sohail Rashid, Mohammad Salih, Abdullah Saeed, Amjad Salamat, Ghias-un-Nabi Tayyab, Aasim Yusuf, Haseeb Haider Zia and Ammara Naveed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ammara Naveed, MBBS, Assistant Professor, Department of Gastroenterology & Hepatology, Pakistan Kidney and Liver Institute & Research Centre, DHA Phase VI Lahore, Lahore 54000, Pakistan. ammara.naveed@pkli.org.pk |
| Key Words |
Hilar cholangiocarcinoma; Bismuth-Corlette classification; Memorial Sloan Kettering Cancer Centre Staging; Preoperative biliary drainage; Portal vein embolisation; Surgical resection; Hepatectomy |
| Core Tip |
Consensus among national hepatobiliary experts convened at the Pakistan Kidney and Liver Institute & Research Centre emphasized the complexity of hilar cholangiocarcinoma (hCCA), advocating a multidisciplinary approach for optimal patient management. Diagnostic protocol includes imaging like computed tomography, magnetic resonance imaging, and magnetic resonance cholangiopancreatography, while endoscopic retrograde cholangiopancreatography plays an important role in tissue acquisition. Surgical resection remains the best curative treatment option. For unresectable cases, liver transplantation is considered under strict selection criteria. Preoperative biliary drainage and portal vein embolisation decisions may be needed for selective cases. Adjuvant chemotherapy addresses the risk of recurrence. The role of Immunotherapy is emerging and offers improved survival for irresectable hCCA. |
| Publish Date |
2024-03-06 06:10 |
| Citation |
Dar FS, Abbas Z, Ahmed I, Atique M, Aujla UI, Azeemuddin M, Aziz Z, Bhatti ABH, Bangash TA, Butt AS, Butt OT, Dogar AW, Farooqi JI, Hanif F, Haider J, Haider S, Hassan SM, Jabbar AA, Khan AN, Khan MS, Khan MY, Latif A, Luck NH, Malik AK, Rashid K, Rashid S, Salih M, Saeed A, Salamat A, Tayyab GUN, Yusuf A, Zia HH, Naveed A. National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma. World J Gastroenterol 2024; 30(9): 1018-1042 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i9/1018.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i9.1018 |
