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2/27/2024 11:58:45 AM | Browse: 62 | Download: 147
Publication Name World Journal of Hepatology
Manuscript ID 90421
Country Brazil
Received
2023-12-03 16:29
Peer-Review Started
2023-12-03 16:30
To Make the First Decision
Return for Revision
2023-12-15 12:32
Revised
2024-01-04 21:52
Second Decision
2024-01-23 02:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-01-23 07:23
Articles in Press
2024-01-23 07:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-02-19 07:00
Publish the Manuscript Online
2024-02-27 11:58
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Advancements in autoimmune hepatitis management: Perspectives for future guidelines
Manuscript Source Invited Manuscript
All Author List Marcos Mucenic
ORCID
Author(s) ORCID Number
Marcos Mucenic http://orcid.org/0000-0001-9389-2236
Funding Agency and Grant Number
Corresponding Author Marcos Mucenic, MD, PhD, Doctor, Medical Assistant, Liver Transplantation Group, Santa Casa de Porto Alegre, Independencia 75, Porto Alegre 90035-070, RS, Brazil. mmucenic@gmail.com
Key Words Autoimmune Hepatitis; Treatment; Immunosuppression; Relapse; Remission induction
Core Tip Autoimmune hepatitis guidelines consider corticosteroids as first-line treatment, including budesonide as an option in patients without cirrhosis. Azathioprine is recommended to reduce corticosteroid doses and side effects. Nevertheless, there are concerns regarding its long-term malignancy risks. Recent publications suggest that these guidelines may be outdated. The efficacy of budesonide can be limited to patients with lower aminotransferases levels. The potential superiority of mycophenolate mofetil to azathioprine is under scrutiny. Additionally, there are controversies regarding treatment suspension, with a potential role for chloroquine for long-term maintenance treatment. Other therapeutic agents are still in the initial stages of research.
Publish Date 2024-02-27 11:58
Citation Mucenic M. Advancements in autoimmune hepatitis management: Perspectives for future guidelines. World J Hepatol 2024; 16(2): 135-139
URL https://www.wjgnet.com/1948-5182/full/v16/i2/135.htm
DOI https://dx.doi.org/10.4254/wjh.v16.i2.135
Full Article (PDF) WJH-16-135-with-cover.pdf
Full Article (Word) WJH-16-135.docx
Manuscript File 90421_Auto_Edited-LJH-YJP.docx
Answering Reviewers 90421-Answering reviewers.pdf
Audio Core Tip 90421-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 90421-Conflict-of-interest statement.pdf
Copyright License Agreement 90421-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 90421-Language certificate.pdf
Peer-review Report 90421-Peer-review(s).pdf
Scientific Misconduct Check 90421-Bing-Liu JH-2.png
Scientific Misconduct Check 90421-CrossCheck.png
Scientific Editor Work List 90421-Scientific editor work list.pdf