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2/26/2024 1:28:46 PM | Browse: 52 | Download: 128
Publication Name World Journal of Gastroenterology
Manuscript ID 91014
Country China
Received
2023-12-20 00:57
Peer-Review Started
2023-12-20 00:57
To Make the First Decision
Return for Revision
2024-01-06 01:35
Revised
2024-01-16 15:14
Second Decision
2024-02-01 02:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-02-01 03:15
Articles in Press
2024-02-01 03:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-02-20 01:15
Publish the Manuscript Online
2024-02-26 13:28
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Evaluating the influence of sarcopenia and myosteatosis on clinical outcomes in gastric cancer patients undergoing immune checkpoint inhibitor
Manuscript Source Unsolicited Manuscript
All Author List Gui-Ming Deng, Hai-Bin Song, Zhong-Ze Du, Ying-Wei Xue, Hong-Jiang Song and Yuan-Zhou Li
ORCID
Author(s) ORCID Number
Gui-Ming Deng http://orcid.org/0000-0003-1415-5356
Ying-Wei Xue http://orcid.org/0000-0002-8427-9736
Yuan-Zhou Li http://orcid.org/0009-0004-1792-2332
Funding Agency and Grant Number
Corresponding Author Yuan-Zhou Li, PhD, Professor, Department of Radiology, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin 150081, Heilongjiang Province, China. 830667@hrbmu.edu.cn
Key Words Gastric cancer; Sarcopenia; Myosteatosis, Immune checkpoint inhibitor; Prognostic factor; Overall survival; Progression-free survival
Core Tip We performed a retrospective study to evaluate the use of sarcopenia and myosteatosis for the prediction of the prognosis of patients with gastric cancer who are being treated with an immune checkpoint inhibitor (ICI). We studied 115 patients with complete sets of clinical data and imaging information and analyzed their muscle cross-sectional area at the L3 Level. We determined the optimal cut-off area value to identify sarcopenia, and myosteatosis was defined using mean skeletal muscle densities of < 41 Hounsfield units (HU) for patients with a body mass index (BMI) < 25 kg/m² and < 33 HU for those with a BMI ≥ 25 kg/m². We found that muscle loss and muscle steatosis are independent predictors of the outcomes of patients with gastric cancer being treated with an ICI.
Publish Date 2024-02-26 13:28
Citation Deng GM, Song HB, Du ZZ, Xue YW, Song HJ, Li YZ. Evaluating the influence of sarcopenia and myosteatosis on clinical outcomes in gastric cancer patients undergoing immune checkpoint inhibitor. World J Gastroenterol 2024; 30(8): 863-880
URL https://www.wjgnet.com/1007-9327/full/v30/i8/863.htm
DOI https://dx.doi.org/10.3748/wjg.v30.i8.863
Full Article (PDF) WJG-30-863-with-cover.pdf
Full Article (Word) WJG-30-863.docx
Manuscript File 91014_Auto_Edited-YJP.docx
Answering Reviewers 91014-Answering reviewers.pdf
Audio Core Tip 91014-Audio core tip.mp3
Biostatistics Review Certificate 91014-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 91014-Conflict-of-interest statement.pdf
Copyright License Agreement 91014-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 91014-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 91014-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 91014-Language certificate.pdf
Peer-review Report 91014-Peer-review(s).pdf
Scientific Misconduct Check 91014-CrossCheck.png
Scientific Misconduct Check 91014-Google-Gong ZM-2.jpg
Scientific Editor Work List 91014-Scientific editor work list.pdf