Publication Name	World Journal of Gastroenterology
Manuscript ID	9537
Country	China

Received	2014-02-16 11:51
Peer-Review Started	2014-02-16 13:12
To Make the First Decision	2014-03-13 18:48
Return for Revision	2014-03-23 17:06
Revised	2014-04-18 21:37
Second Decision	2014-05-29 20:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-29 20:26
Articles in Press	2014-05-29 21:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-06-18 06:50
Typeset the Manuscript	2014-09-26 09:56
Publish the Manuscript Online	2014-10-16 15:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population
Manuscript Source	Unsolicited Manuscript
All Author List	Min-Rui Li, Sheng-Hong Zhang, Kang Chao, Xian-Hua Liao, Jia-Yan Yao, Min-Hu Chen and Bi-Hui Zhong
Funding Agency and Grant Number	Funding Agency Grant Number Natural Scientific Foundation of Guangdong Province S2012040007685 Doctoral Program Foundation of Institutions of Higher Education of China 20120171120090 National Natural Science Foundation of China 81301769 National Natural Science Foundation of China 81170392
Corresponding Author	Bi-Hui Zhong, MD, PhD, Division of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan Road II, Guangzhou 510080, Guangdong Province, China. sophiazhong@medmail.com.cn
Key Words	Apolipoprotein C3; Nonalcoholic fatty liver disease; Insulin resistance; Metabolic disorder; Polymorphism
Core Tip	This study represents the first study to investigate the relationship between the Apolipoprotein C3 (APOC3) (-455T>C) polymorphism and nonalcoholic fatty liver disease (NAFLD) susceptibility in the Southern Chinese Han population. After adjusting for age, gender, and body-mass index, we found that APOC3 (-455T>C) genetic variation was involved in the susceptibility to developing NAFLD, insulin resistance, hypertension, hypertriglyceridemia, and low high-density lipoprotein cholesterol. In the additive genetic model, carriers of variant-type homozygote CC showed the highest susceptibility to the above disorders, followed by carriers of heterozygote TC and wild-type homozygote TT.
Publish Date	2014-10-16 15:53
Citation	Li MR, Zhang SH, Chao K, Liao XH, Yao YJ, Chen MH, Zhong BH. Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the southern Han Chinese population. World J Gastroenterol 2014; 20(38): 14010-14017
URL	http://www.wjgnet.com/1007-9327/full/v20/i38/14010.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i38.14010

Full Article (PDF)	WJG-20-14010.pdf
Full Article (Word)	WJG-20-14010.doc
Manuscript File	9537-Review.docx
Answering Reviewers	9537-Answering reviewers.pdf
Copyright License Agreement	9537-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9537-Language certificate.pdf
Peer-review Report	9537-Peer review(s).pdf
Scientific Misconduct Check	9537-CrossCheck.jpg
Scientific Editor Work List	9537-Scientific editor work list.pdf