Publication Name	World Journal of Hypertension
Manuscript ID	14501
Country	Spain

Received	2014-10-08 08:46
Peer-Review Started	2014-10-08 17:59
To Make the First Decision	2014-10-28 14:24
Return for Revision	2014-11-01 19:26
Revised	2014-11-12 18:37
Second Decision	2014-11-28 14:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-10 17:22
Articles in Press	2014-12-10 17:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-28 19:06
Publish the Manuscript Online	2015-02-12 10:27

ISSN	2220-3168 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Contribution of miRNAs to ion-channel remodelling in atrial fibrillation
Manuscript Source	Invited Manuscript
All Author List	José Manuel Vilches, Diego Franco and Amelia E Aránega
Funding Agency and Grant Number	Funding Agency Grant Number Ministerio de Economíay Competitividad, Gobierno de España BFU2012-38111 Junta de Andalucia CTS-1614 Junta de Andalucia P08-CTS-03878 Junta de Andalucia BIO-302 AFM AFM2012-16074
Corresponding Author	Amelia E Aránega, PhD, Cardiac and Skeletal Myogenesis Group, Department of Experimental Biology, University of Jaén, CU Las Lagunillas B3-362, 23071 Jáen, Spain. aaranega@ujaen.es
Key Words	Atrial fibrillation; MicroRNA; Ion channels; Electrical remodelling
Core Tip	Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice associated with pronounced mortality and morbidity. MicroRNAs (miRNAs), which are approximately 22 nucleotide long RNA regulators of gene expression, have become a major focus of research in molecular biology miRNAs have emerged as key post-transcriptional regulators of gene expression therefore, it is important to comment on the roles of these small non-protein-coding mRNAs in the cardiovascular system and their involvement in AF. In this review, we summarize the mechanism of miRNAs as regulators of ion-channels genes and their role in electrical remodelling caused by AF.
Publish Date	2015-02-12 10:27
Citation	Vilches JM, Franco D, Aránega AE. Contribution of miRNAs to ion-channel remodelling in atrial fibrillation. World J Hypertens 2015; 5(1): 6-13
URL	http://www.wjgnet.com/2220-3168/full/v5/i1/6.htm
DOI	http://dx.doi.org/10.5494/wjh.v5.i1.6

Full Article (PDF)	WJH-5-6.pdf
Full Article (Word)	WJH-5-6.doc
Manuscript File	14501-Review.docx
Answering Reviewers	14501-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14501-Conflict-of-interest statement.pdf
Copyright License Agreement	14501-Copyright assignment.pdf
Peer-review Report	14501-Peer review(s).pdf
Scientific Misconduct Check	14501-CrossCheck.jpg
Scientific Editor Work List	14501-Scientific editor work list.pdf