Publication Name	World Journal of Stem Cells
Manuscript ID	22478
Country	Belgium

Received	2015-08-29 15:50
Peer-Review Started	2015-09-06 15:47
To Make the First Decision	2015-11-06 10:53
Return for Revision	2015-11-11 17:38
Revised	2015-12-24 00:00
Second Decision	2016-01-20 16:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-01-29 17:35
Articles in Press	2016-01-29 17:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-02 10:34
Publish the Manuscript Online	2016-03-21 08:20

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishin Group Inc. All rights reserved.
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Category	Hematology
Manuscript Type	Review
Article Title	Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?
Manuscript Source	Invited Manuscript
All Author List	Ann De Becker and Ivan Van Riet
Funding Agency and Grant Number
Corresponding Author	Ivan Van Riet, MSc, PhD, Department Clinical Hematology-Stem Cell Laboratory, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090 Jette, Belgium. ivan.vanriet@uzbrussel.be
Key Words	Mesenchymal stromal cells; Homing; Bone marrow; Homing receptors; Extravasation
Core Tip	Mesenchymal stromal cells (MSCs) are currently under investigation for use in a variety of clinical applications. In most studies, MSCs are administered systemically. This requires efficient homing and migration of the MSCs to a target tissue. However, the homing mechanisms of MSCs are not completely understood. Moreover, the in vivo homing and migration of MSCs does not appear to be highly efficient. Therefore, different methods have been investigated to improve homing. Here, we will review the current knowledge of bone marrow homing of MSCs, as well as the different strategies that might improve the homing capacity of these stem cells.
Publish Date	2016-03-21 08:20
Citation	De Becker A, Van Riet I. Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy? World J Stem Cells 2016; 8(3): 73-87
URL	http://www.wjgnet.com/1948-0210/full/v8/i3/73.htm
DOI	http://dx.doi.org/10.4252/wjsc.v8.i3.73

Full Article (PDF)	WJSC-8-73.pdf
Full Article (Word)	WJSC-8-73.doc
Manuscript File	22478-Review.docx
Answering Reviewers	22478-Answering reviewers.pdf
Audio Core Tip	22478-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	22478-Conflict-of-interest statement.pdf
Copyright License Agreement	22478-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22478-Language certificate.pdf
Peer-review Report	22478-Peer-review(s).pdf
Scientific Misconduct Check	22478-Scientific misconduct check.pdf
Scientific Editor Work List	22478-Scientific editor work list.pdf