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9/28/2016 3:08:00 PM | Browse: 534 | Download: 1034
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Received |
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2016-05-27 18:21 |
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Peer-Review Started |
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2016-05-28 18:25 |
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To Make the First Decision |
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2016-07-04 15:48 |
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Return for Revision |
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2016-07-06 08:56 |
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Revised |
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2016-07-15 04:59 |
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Second Decision |
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2016-07-28 14:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-08-08 14:40 |
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Articles in Press |
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2016-08-08 14:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-08-12 17:22 |
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Publish the Manuscript Online |
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2016-08-19 16:02 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Review |
Article Title |
Therapy-related myeloid neoplasms - what have we learned so far?
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Manuscript Source |
Invited Manuscript |
All Author List |
Mohammad Faizan Zahid, Aric Parnes, Bipin N Savani, Mark R Litzow and Shahrukh K Hashmi |
Funding Agency and Grant Number |
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Corresponding Author |
Mohammad Faizan Zahid, MBBS, Medical College, Aga Khan University, P.O. Box 3500, Stadium road, Karachi 74800, Pakistan. faizanzahid91@hotmail.com |
Key Words |
Therapy-related acute myeloid leukemia; Therapy-related myelodysplastic syndromes; Ionizing radiation; Alkylating agents; Allogeneic hematopoietic stem cell transplantation; Topoisomerase Ⅱ inhibitors; Therapy-related myeloid neoplasms |
Core Tip |
Therapy-related myeloid neoplasms are becom-ing an increasing problem as the survival of cancer patients lengthens. The etiology has an important in-fluence on the biological characteristics, time to onset and prognosis of the resultant disease. Although treatment of therapy-related myeloid neoplasms represents a substantial challenge due to prior treatment and comorbidities, cure is possible, especially with allogeneic stem cell transplantation, particularly in those with good-risk karyotype. Ultimately, individual assessment of risk factors may lead to developing risk-adapted therapies to reduce the incidence of this serious complication without affecting therapy for the underlying disorders. |
Publish Date |
2016-08-19 16:02 |
Citation |
Zahid MF, Parnes A, Savani BN, Litzow MR, Hashmi SK. Therapy-related myeloid neoplasms - what have we learned so far? World J Stem Cells 2016; 8(8): 231-242 |
URL |
http://www.wjgnet.com/1948-0210/full/v8/i8/231.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v8.i8.231 |
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