Publication Name	World Journal of Hepatology
Manuscript ID	29828
Country	Canada

Received	2016-08-29 14:58
Peer-Review Started	2016-08-29 23:16
First Decision by Editorial Office Director
Return for Revision	2016-11-21 16:55
Revised	2016-12-20 06:01
Publication Fee Transferred
Second Decision by Editor	2017-04-10 17:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2017-04-20 08:28
Articles in Press	2017-04-20 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-15 00:19
Publish the Manuscript Online	2017-05-17 06:29

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http: //creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Strategies to tackle the challenges of external beam radiotherapy for liver tumors
Manuscript Source	Invited Manuscript
All Author List	Michael I Lock, Jonathan Klein, Hans T Chung, Joseph M Herman, Edward Y Kim, William Small, Nina A Mayr and Simon S Lo
Funding Agency and Grant Number
Corresponding Author	Michael I Lock, MD, CCFP, FRCPC, FCFP, Department of Radiation Oncology, London Regional Cancer Program, University of Western Ontario, 790 Commissioners Rd East, London, ON N6A 3K7, Canada. michael.lock@lhsc.on.ca
Key Words	Hepatocellular carcinoma; Liver metastases; 4DCT; Image-guided radiotherapy; Stereotactic body radiation therapy
Core Tip	Primary and metastatic liver cancer patients are a growing population seen in cancer centers. This population often has few options and a poor prognosis. Radiation offers a safe non-invasive treatment option, but those implementing a liver radiotherapy program must address specific challenges not always seen in other disease sites. A growing and large number of papers have investigated a wide range of strategies. Our objective is to consolidate this literature to provide a concise review of options to allow a pragmatic selection of management strategies.
Publish Date	2017-05-17 06:29
Citation	Lock MI, Klein J, Chung HT, Herman JM, Kim EY, Small W, Mayr NA, Lo SS. Strategies to tackle the challenges of external beam radiotherapy for liver tumors. World J Hepatol 2017; 9(14): 645-656
URL	http://www.wjgnet.com/1948-5182/full/v9/i14/645.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i14.645

Full Article (PDF)	WJH-9-645.pdf
Full Article (Word)	WJH-9-645.doc
Manuscript File	29828-Review.docx
Answering Reviewers	29828-Answering reviewers.pdf
Audio Core Tip	29828-Audio core tip.wma
Conflict-of-Interest Disclosure Form	29828-Conflict-of-interest statement.pdf
Copyright License Agreement	29828-Copyright assignment.pdf
Peer-review Report	29828-Peer-review(s).pdf
Scientific Misconduct Check	29828-Scientific misconduct check.pdf
Scientific Editor Work List	29828-Scientific editor work list.pdf