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3/20/2018 8:52:28 AM | Browse: 831 | Download: 621
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Received |
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2018-01-27 12:52 |
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Peer-Review Started |
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2018-01-28 09:52 |
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To Make the First Decision |
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2018-02-10 08:26 |
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Return for Revision |
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2018-02-11 04:20 |
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Revised |
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2018-02-12 09:31 |
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Second Decision |
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2018-02-25 10:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-02-25 23:02 |
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Articles in Press |
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2018-02-25 23:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-03-05 22:09 |
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Typeset the Manuscript |
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2018-03-15 09:11 |
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Publish the Manuscript Online |
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2018-03-16 12:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Functional macrophages and gastrointestinal disorders
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yue-Hong Liu, Yue Ding, Chen-Chen Gao, Li-Sheng Li, Yue-Xiu Wang and Jing-Dong Xu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81274173 |
| National Natural Science Foundation of China |
81673671 |
| National Natural Science Foundation of China |
81270443 |
| Beijing National Science Foundation |
7122017 |
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| Corresponding Author |
Jing-Dong Xu, PhD, Assistant Professor, School of Basic Medical Sciences, Beijing Capital Medical University, No.10, Xitoutiao, Youanmenwai, Fengtai district, Beijing 100069, China. xujingdong@163.com |
| Key Words |
Macrophages; Homeostasis; Inflammatory bowel disease; Gastrointestinal tumors; Therapeutic targets |
| Core Tip |
The manuscript involves three components. First, after briefly describing the origin of macrophages (MΦ), it summarizes their general biologic features and common functions. The second component reveals the differences between resident MΦ in the intestine and those in other tissues. Notably, we depicted how resident MΦ participate in maintaining intestinal homeostasis and why they can maintain intestinal health by comparison between each of these distinct features. The third part discusses how the deficiency of this anti-inflammatory system leads to autoimmune diseases. However, we also discuss the many details of why intestinal MΦ and the underlying mechanism of inflammatory bowel disease and gut tumors remain obscure. |
| Publish Date |
2018-03-16 12:27 |
| Citation |
Liu YH, Ding Y, Gao CC, Li LS, Wang YX, Xu JD. Functional macrophages and gastrointestinal disorders. World J Gastroenterol 2018; 24(11): 1181-1195 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i11/1181.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i11.1181 |
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