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10/29/2018 12:59:07 AM | Browse: 1343 | Download: 1711
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Received |
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2018-07-27 12:51 |
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Peer-Review Started |
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2018-07-29 10:52 |
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To Make the First Decision |
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2018-08-31 00:30 |
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Return for Revision |
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2018-09-03 02:22 |
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Revised |
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2018-09-05 21:14 |
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Second Decision |
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2018-09-29 08:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-10-13 02:02 |
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Articles in Press |
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2018-10-13 02:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-10-20 09:00 |
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Publish the Manuscript Online |
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2018-10-22 09:50 |
ISSN |
2220-3192 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Pharmacology & Pharmacy |
Manuscript Type |
Editorial |
Article Title |
Kv7 channels a potential therapeutic target in fibromyalgia: A hypothesis
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Manuscript Source |
Invited Manuscript |
All Author List |
Kim Lawson |
Funding Agency and Grant Number |
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Corresponding Author |
Kim Lawson, PhD, Senior Lecturer, Department of Biosciences and Chemistry, Biomolecular Sciences Research Centre, Sheffield Hallam University, City Campus, Howard Street, Sheffield S1 1WB, United Kingdom. k.lawson@shu.ac.uk |
Key Words |
Fibromyalgia; Persistent pain; Potassium channels; Kv7 channels; Flupirtine; Retigabine |
Core Tip |
Fibromyalgia a multifaceted disorder remains a major unmet condition with current therapies providing limited control. An involvement of potassium channels in the pathophysiology of fibromyalgia and the related symptoms is emerging, and Kv7 channel activators, such as flupirtine and retigabine, exhibit pharmacological profiles compatible with the requirements of therapeutic approaches to fibromyalgia. Focused clinical trials with flupirtine and retigabine will provide important insight to the role of potassium channels and the utility of Kv7 channel activators in fibromyalgia. |
Publish Date |
2018-10-22 09:50 |
Citation |
Lawson K. Kv7 channels a potential therapeutic target in fibromyalgia: A hypothesis. World J Pharmacol 2018; 7(1): 1-9 |
URL |
http://www.wjgnet.com/2220-3192/full/v7/i1/1.htm |
DOI |
http://dx.doi.org/10.5497/wjp.v7.i1.1 |
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