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2/28/2020 10:02:29 AM | Browse: 480 | Download: 720
Publication Name World Journal of Stem Cells
Manuscript ID 50082
Country United States
Received
2019-07-05 01:09
Peer-Review Started
2019-07-17 08:50
To Make the First Decision
2019-08-28 05:23
Return for Revision
2019-09-02 09:40
Revised
2019-12-03 08:32
Second Decision
2019-12-21 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-23 22:49
Articles in Press
2019-12-23 22:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-01-01 18:12
Typeset the Manuscript
2020-02-24 05:30
Publish the Manuscript Online
2020-02-27 07:06
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Basic Study
Article Title Clonal isolation of endothelial colony forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration
Manuscript Source Invited Manuscript
All Author List Kewa Gao, Siqi He, Priyadarsini Kumar, Diana Farmer, Jianda Zhou and Aijun Wang
Funding Agency and Grant Number
Funding Agency Grant Number
UC Davis School of Medicine Dean’s Fellowship award PC1-08103
California Institute of Regenerative Medicine CLIN1-11404
Shriners Hospital for Children 85120-NCA-16
Shriners Hospital for Children 85119-NCA-18
Shriners Hospital for Children 85108-NCA-19
Shriners Hospital for Children 87200-NCA-19
March of Dimes Foundation 5FY1682
Corresponding Author Aijun Wang, PhD, Associate Professor, Surgical Bioengineering Laboratory, Department of Surgery, University of California, Davis School of Medicine, 4625 2nd Ave., Room 3005, Sacramento, CA 95817, United States. aawang@ucdavis.edu
Key Words Placenta; Endothelial colony forming cells; Chorionic villi; Angiogenesis; Tissue engineering;
Core Tip We established a magnetic sorting assisted clonal isolation protocol to derive chronic villi endothelial colony forming cells (CV-ECFCs) from early gestation placentas. Using our protocol, a substantial number of CV-ECFCs can be obtained from chorionic villus sampling (CVS) size placental tissue within a short time frame, making it feasible for autologous fetal treatment. CV-ECFCs are comparable to umbilical cord blood-derived endothelial colony forming cells (CB-ECFCs) in terms of surface marker expression, tube formation capacity, transducability, and compatibility with biomaterial delivery vehicles. CV-ECFCs represent a novel autologous source of cells for fetal or postnatal treatment of congenital anomalies or defects.
Publish Date 2020-02-27 07:06
Citation Gao KW, He SQ, Kumar P, Farmer D, Zhou JD, Wang AJ. Clonal isolation of endothelial colony forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration. World J Stem Cells 2020; 12(2): 123-138
URL https://www.wjgnet.com/1948-0210/full/v12/i2/123.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i2.123
Full Article (PDF) WJSC-12-123.pdf
Full Article (Word) WJSC-12-123.docx
Manuscript File 50082-Review.docx
Answering Reviewers 50082-Answering reviewers.pdf
Audio Core Tip 50082-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 50082-Conflict-of-interest statement.pdf
Copyright License Agreement 50082-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 50082-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 50082-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 50082-Language certificate.pdf
Peer-review Report 50082-Peer-review(s).pdf
Scientific Misconduct Check 50082-Scientific misconduct check.pdf
Scientific Editor Work List 50082-Scientific editor work list.pdf