BPG is committed to discovery and dissemination of knowledge
Featured Articles
1/14/2020 2:35:12 AM | Browse: 165 | Download: 105
Publication Name World Journal of Stem Cells
Manuscript ID 50798
Country/Territory Germany
Received
2019-08-09 09:56
Peer-Review Started
2019-08-09 09:56
To Make the First Decision
2019-09-05 00:57
Return for Revision
2019-09-12 06:39
Revised
2019-11-25 16:27
Second Decision
2019-12-13 12:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-16 03:58
Articles in Press
2019-12-16 03:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-12-24 07:03
Publish the Manuscript Online
2019-12-30 01:55
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Review
Article Title Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish
Manuscript Source Invited Manuscript
All Author List Alessandro Zambusi and Jovica Ninkovic
Funding Agency and Grant Number
Funding Agency Grant Number
the German Research foundation (DFG) SFB 870
Corresponding author Jovica Ninkovic, PhD, Professor, Research Scientist, Helmholtz Center Munich, Biomedical Center, Inst Stem Cell Res, Institute of Stem Cell Research, University of Munich, Grosshadernerstrasse 9, Planegg 82152, Germany. ninkovic@helmholtz-muenchen.de
Keywords Zebrafish; Central nervous system; Brain injury; Glial scar; Regeneration; Restorative neurogenesis
Core Tip Poor recovery of neuronal functions is one of the most common healthcare challenges for patients with different types of brain injuries. In contrast to mammals, zebrafish have developed specific mechanisms to activate a restorative neurogenic program in a specific set of glial cells (ependymoglia) and to resolve both the glial scar and inflammation, thus enabling proper neuronal specification and survival. In this review, we discuss these mechanisms and their potential applicability for the repair of the mammalian central nervous system.
Publish Date 2019-12-30 01:55
Citation Zambusi A, Ninkovic J. Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish. World J Stem Cells 2020; 12(1): 8-24
Url https://www.wjgnet.com/1948-0210/full/v12/i1/8.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i1.8
Full Article (PDF) WJSC-12-8.pdf
Full Article (Word) WJSC-12-8.docx
Manuscript File 50798-Review.docx
Answering Reviewers 50798-Answering reviewers.pdf
Audio Core Tip 50798-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 50798-Conflict-of-interest statement.pdf
Copyright License Agreement 50798-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 50798-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 50798-Language certificate.pdf
Peer-review Report 50798-Peer-review(s).pdf
Scientific Misconduct Check 50798-Scientific misconduct check.pdf
Scientific Editor Work List 50798-Scientific editor work list.pdf