Publication Name	World Journal of Stem Cells
Manuscript ID	50798
Country	Germany

Received	2019-08-09 09:56
Peer-Review Started	2019-08-09 09:56
To Make the First Decision	2019-09-05 00:57
Return for Revision	2019-09-12 06:39
Revised	2019-11-25 16:27
Second Decision	2019-12-13 12:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-12-16 03:58
Articles in Press	2019-12-16 03:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-24 07:03
Publish the Manuscript Online	2019-12-30 01:55

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish
Manuscript Source	Invited Manuscript
All Author List	Alessandro Zambusi and Jovica Ninkovic
Funding Agency and Grant Number	Funding Agency Grant Number the German Research foundation (DFG) SFB 870
Corresponding Author	Jovica Ninkovic, PhD, Professor, Research Scientist, Helmholtz Center Munich, Biomedical Center, Inst Stem Cell Res, Institute of Stem Cell Research, University of Munich, Grosshadernerstrasse 9, Planegg 82152, Germany. ninkovic@helmholtz-muenchen.de
Key Words	Zebrafish; Central nervous system; Brain injury; Glial scar; Regeneration; Restorative neurogenesis
Core Tip	Poor recovery of neuronal functions is one of the most common healthcare challenges for patients with different types of brain injuries. In contrast to mammals, zebrafish have developed specific mechanisms to activate a restorative neurogenic program in a specific set of glial cells (ependymoglia) and to resolve both the glial scar and inflammation, thus enabling proper neuronal specification and survival. In this review, we discuss these mechanisms and their potential applicability for the repair of the mammalian central nervous system.
Publish Date	2019-12-30 01:55
Citation	Zambusi A, Ninkovic J. Regeneration of the central nervous system-principles from brain regeneration in adult zebrafish. World J Stem Cells 2020; 12(1): 8-24
URL	https://www.wjgnet.com/1948-0210/full/v12/i1/8.htm
DOI	https://dx.doi.org/10.4252/wjsc.v12.i1.8

Full Article (PDF)	WJSC-12-8.pdf
Full Article (Word)	WJSC-12-8.docx
Manuscript File	50798-Review.docx
Answering Reviewers	50798-Answering reviewers.pdf
Audio Core Tip	50798-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	50798-Conflict-of-interest statement.pdf
Copyright License Agreement	50798-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	50798-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	50798-Language certificate.pdf
Peer-review Report	50798-Peer-review(s).pdf
Scientific Misconduct Check	50798-Scientific misconduct check.pdf
Scientific Editor Work List	50798-Scientific editor work list.pdf
CrossCheck Report	50798-CrossCheck report.pdf