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8/12/2020 10:38:05 AM | Browse: 374 | Download: 584
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Received |
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2020-02-10 05:16 |
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Peer-Review Started |
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2020-02-10 05:18 |
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To Make the First Decision |
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Return for Revision |
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2020-03-24 14:39 |
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Revised |
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2020-04-06 17:32 |
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Second Decision |
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2020-06-16 09:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-06-17 20:23 |
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Articles in Press |
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2020-06-17 20:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-06-22 09:09 |
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Typeset the Manuscript |
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2020-07-21 14:40 |
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Publish the Manuscript Online |
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2020-08-12 09:10 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Identification of an immune-related gene-based signature to predict prognosis of patients with gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xiang-Ting Qiu, Yu-Cui Song, Jian Liu, Zhen-Min Wang, Xing Niu and Jing He |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jing He, MD, PhD, Professor, Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No. 9 Jinsui Road, Guangzhou 510623, Guangdong Province, China. hejing198374@gmail.com |
| Key Words |
Gastric cancer; Immune-related genes; Tumor microenvironment; Immune infiltration; Prognosis; Signature |
| Core Tip |
Gastric cancer (GC) is the most commonly diagnosed malignancy worldwide. Increasing evidence suggests that it is necessary to further explore genetic and immunological characterization of GC. Our study conducted an immune-related prognostic signature for GC, which could accurately distinguish patients into high- and low- risk groups. High risk patients had poorer prognosis. After multivariate Cox regression analysis, the prognostic signature could independently predict GC prognosis. Furthermore, it was significantly associated with immune cell infiltration (especially macrophages). Therefore, the signature may possess prognostic value as a prediction tool for identification of patients who will benefit from immunotherapy. |
| Publish Date |
2020-08-12 09:10 |
| Citation |
Qiu XT, Song YC, Liu J, Wang ZM, Niu X, He J. Identification of an immune-related gene-based signature to predict prognosis of patients with gastric cancer. World J Gastrointest Oncol 2020; 12(8): 857-876 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i8/857.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i8.857 |
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