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10/18/2020 1:35:14 PM | Browse: 387 | Download: 606
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Received |
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2020-06-02 15:04 |
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Peer-Review Started |
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2020-06-02 15:05 |
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To Make the First Decision |
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Return for Revision |
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2020-07-04 21:52 |
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Revised |
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2020-07-15 18:59 |
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Second Decision |
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2020-09-10 09:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-09-10 17:51 |
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Articles in Press |
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2020-09-10 17:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-10-16 13:58 |
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Publish the Manuscript Online |
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2020-10-18 13:28 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Clinical Neurology |
| Manuscript Type |
Case Report |
| Article Title |
Long-term effect of intrathecal baclofen treatment on bone health and body composition after spinal cord injury: A case matched report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dora E Ifon, Mina P Ghatas, John C Davis, Refka E Khalil, Robert A Adler and Ashraf S Gorgey |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| DoD-CDRMP |
W81XWH-14-SCIRP-CTA |
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| Corresponding Author |
Ashraf S Gorgey, PhD, Physiotherapist, Professor, Spinal Cord Injury and Disorders Center, Central Virginia VA Health Care System, 1201 Broad Rock Boulevard, Richmond, VA 23249, United States. ashraf.gorgey@va.gov |
| Key Words |
Intrathecal baclofen; Spasticity; Bone mineral density; Epiphysis; Metaphysis; Spinal cord injury |
| Core Tip |
The long-term effects of intrathecal baclofen treatment (IBT) on bone mineral density and body composition profile were investigated in a man with spinal cord injury compared to two matched participants with different age and time since injury. Bone mineral density loss was greater at the distal femur and proximal tibia compared to the matches without IBT. Furthermore, the case had greater percentage leg fat mass and lower percentage lean mass compared to both matches. The negative side effects of IBT implantation warrant further studies considering the prevalence of osteoporosis related fractures, cardiovascular diseases, and metabolic disorders in this population. |
| Publish Date |
2020-10-18 13:28 |
| Citation |
Ifon DE Ghatas MP, Davis JC, Khalil RE, Adler RA, Gorgey AS. Long-term effect of intrathecal baclofen treatment on bone health and body composition after spinal cord injury: A case matched report. World J Orthop 2020; 11(10): 453-464 |
| URL |
https://www.wjgnet.com/2218-5836/full/v11/i10/453.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v11.i10.453 |
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