Publication Name	World Journal of Gastroenterology
Manuscript ID	60414
Country	China

Received	2020-11-20 07:16
Peer-Review Started	2020-11-20 07:17
To Make the First Decision
Return for Revision	2021-01-23 18:50
Revised	2021-02-02 22:33
Second Decision	2021-02-22 09:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-02-25 17:22
Articles in Press	2021-02-25 17:22
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-08 04:34
Typeset the Manuscript	2021-03-23 02:31
Publish the Manuscript Online	2021-03-25 11:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	R2* value derived from multi-echo Dixon technique can aid discrimination between benign and malignant focal liver lesions
Manuscript Source	Unsolicited Manuscript
All Author List	Guang-Zi Shi, Hong Chen, Wei-Ke Zeng, Ming Gao, Meng-Zhu Wang, Hui-Ting Zhang and Jun Shen
Funding Agency and Grant Number
Corresponding Author	Jun Shen, MD, Doctor, Professor, Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong Province, China. shenjun@mail.sysu.edu.cn
Key Words	R2*; Multi-echo Dixon imaging; Hypoxia; Malignant lesion; Benign lesion; Focal liver lesion
Core Tip	Our study showed that mean R2* value of malignant focal liver lesions (FLLs) was significantly higher than that of the benign FLLs. R2* derived from multi-echo Dixon imaging is a potential biomarker to differentiate malignant from benign FFLs. The multi-echo Dixon sequence is easy to perform and required only a single breath-hold of 16 s to image the entire liver, which holds a good potential for clinical application.
Publish Date	2021-03-25 11:42
Citation	Shi GZ, Chen H, Zeng WK, Gao M, Wang MZ, Zhang HT, Shen J. R2* value derived from multi-echo Dixon technique can aid discrimination between benign and malignant focal liver lesions. World J Gastroenterol 2021; 27(12): 1182-1193
URL	https://www.wjgnet.com/1007-9327/full/v27/i12/1182.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i12.1182

Full Article (PDF)	WJG-27-1182.pdf
Full Article (Word)	WJG-27-1182.docx
Manuscript File	60414_Auto_Edited_LM_WangTQ.docx
Answering Reviewers	60414-Answering reviewers.pdf
Audio Core Tip	60414-Audio core tip.wav
Biostatistics Review Certificate	60414-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	60414-Conflict-of-interest statement.pdf
Copyright License Agreement	60414-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	60414-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	60414-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	60414-Language certificate.pdf
Peer-review Report	60414-Peer-review(s).pdf
Peer-review Report	60414-Scientific editor work list.pdf
Scientific Misconduct Check	60414-Bing-Yan JP-1.png
Scientific Misconduct Check	60414-Scientific misconduct check.pdf