| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Opinion Review |
| Article Title |
Could gastrointestinal tumor-initiating cells originate from cell-cell fusion in vivo?
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Zhou, Jun-Ting Cheng, Zi-Xian Feng, Ying-Ying Wang, Ying Zhang, Wen-Qi Cai, Zi-Wen Han, Xian-Wang Wang, Ying Xiang, Hui-Yu Yang, Bing-Rong Liu, Xiao-Chun Peng, Shu-Zhong Cui and Hong-Wu Xin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81872412 |
| National Natural Science Foundation of China |
81602303 |
| National Natural Science Foundation of China |
31700736 |
| Hubei Province Natural Science Foundation of China |
2016CFB180 |
| Health and Family Planning Commission of Hubei Province |
WJ2016Y07 |
| Hubei Province Scientific and Technological Research Project |
Q20171306 |
| Jingzhou Science and Technology Development Planning Project |
JZKJ15063 |
| Guangzhou Key Medical Discipline Construction Project (CSZ), National Innovation and Entrepreneurship Training Program for College Students |
202010489017 |
| Hubei Province Health and Family Planning Scientific Research Project |
WJ2016-Y-10 |
| Hubei Province Natural Science Foundation of China |
2017CFB786 |
|
| Corresponding Author |
Hong-Wu Xin, MD, PhD, Doctor, Laboratory of Oncology, Center for Molecular Medicine, School of Basic Medicine, Health Science Center, Yangtze University, No. 1 Nanhuan Road, Jingzhou 434023, Hubei Province, China. hongwu_xin@126.com |
| Key Words |
Gastrointestinal tumor initiating cell; Stem cell; Bone marrow-derived cells; In vivo; Cell-cell fusion; In vitro |
| Core Tip |
Currently, there are many controversial hypotheses concerning the generation of gastrointestinal tumor-initiating cells (giTICs). Here, we mainly reviewed the current advances in the understanding of giTIC origination from the cell-cell fusion of cancer cells and bone marrow-derived cells. |
| Publish Date |
2021-02-01 11:01 |
| Citation |
Zhou Y, Cheng JT, Feng ZX, Wang YY, Zhang Y, Cai WQ, Han ZW, Wang XW, Xiang Y, Yang HY, Liu BR, Peng XC, Cui SZ, Xin HW. Could gastrointestinal tumor-initiating cells originate from cell-cell fusion in vivo? World J Gastrointest Oncol 2021; 13(2): 92-108 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i2/92.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i2.92 |
