ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Clinical and Translational Research |
Article Title |
Circulating tumor cells with epithelial-mesenchymal transition markers as the potential biomarker for the diagnosis of lung cancer
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Sha-Sha Jiang, Chun-Guo Mao, Yong-Geng Feng, Bin Jiang, Shao-Lin Tao, Qun-You Tan and Bo Deng |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81572285 |
The Natural Science Foundation of Chongqing City |
2018jcyjAX0592 |
The Army Medical University Clinical Medical Research Talent Training Program |
2018XLC3062 |
|
Corresponding Author |
Bo Deng, MD, PhD, Professor, Surgeon, Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Army Medical University, No. 10 Changjiang Branch St, Yuzhong District, Chongqing 400042, China. dengbo@tmmu.edu.cn |
Key Words |
Circulating tumor cells; Epithelial-to-mesenchymal transition; Diagnosis; Lung cancer; Ground-glass opacities; CanPatrol |
Core Tip |
Circulating tumor cells (CTCs) with epithelial markers (E-CTCs), CTCs with mesenchymal markers (M-CTCs), and CTCs with both markers (E&M-CTCs) can be identified in CTCs, respectively. Therefore, a total of CTCs were clustered into three subtypes, as per the markers of CTCs, i.e., E-CTCs, M-CTCs and E&M-CTCs. Detection of E&M-CTCs had good diagnostic value in distinguishing lung cancer from controls. |
Publish Date |
2021-04-15 04:26 |
Citation |
Jiang SS, Mao CG, Feng YG, Jiang B, Tao SL, Tan QY, Deng B. Circulating tumor cells with epithelial-mesenchymal transition markers as the potential biomarker for the diagnosis of lung cancer. World J Clin Cases 2021; 9(12): 2721-2730 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i12/2721.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i12.2721 |