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4/8/2021 11:33:07 AM | Browse: 274 | Download: 487
Publication Name World Journal of Transplantation
Manuscript ID 61030
Country/Territory United Kingdom
Received
2020-11-22 03:54
Peer-Review Started
2020-11-22 03:55
To Make the First Decision
Return for Revision
2021-01-11 05:22
Revised
2021-01-22 10:47
Second Decision
2021-03-19 11:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-19 16:57
Articles in Press
2021-03-19 16:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-03-29 13:17
Publish the Manuscript Online
2021-04-08 10:21
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Minireviews
Article Title Does steroid-free immunosuppression improve the outcome in kidney transplant recipients compared to conventional protocols?
Manuscript Source Invited Manuscript
All Author List Ahmed Aref, Ajay Sharma and Ahmed Halawa
Funding Agency and Grant Number
Corresponding Author Ahmed Halawa, FRCS (Gen Surg), MSc, Surgeon, Department of Transplantation, Sheffield Teaching Hospitals, Herries Road, Sheffield S5 7AU, United Kingdom. ahmed.halawa@sth.nhs.uk
Key Words Kidney transplantation; Steroid free; Immune suppression; Steroid avoidance; Steroid withdrawal; Outcome
Core Tip Prolonged steroid therapy was associated with many complications that ranged from cosmetic changes to life-threatening increase in cardiovascular risk profile. The utilisation of antibody induction, together with calcineurin inhibitors maintenance immune suppression, had markedly reduced the incidence of acute rejection. The improved rate of acute rejection encouraged different transplant centres to adopt new steroid-free protocols, especially in fragile cases with multiple comorbidities. Variable steroid-free approaches were tried. We aim to explore the safety and efficacy of various steroid-free protocols by comparing each different modality with the conventional triple immune suppression.
Publish Date 2021-04-08 10:21
Citation Aref A, Sharma A, Halawa A. Does steroid-free immunosuppression improve the outcome in kidney transplant recipients compared to conventional protocols? World J Transplant 2021; 11(4): 99-113
URL https://www.wjgnet.com/2220-3230/full/v11/i4/99.htm
DOI https://dx.doi.org/10.5500/wjt.v11.i4.99
Full Article (PDF) WJT-11-99.pdf
Full Article (Word) WJT-11-99.docx
Manuscript File 61030_Auto_Edited_LM.docx
Answering Reviewers 61030-Answering reviewers.pdf
Audio Core Tip 61030-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 61030-Conflict-of-interest statement.pdf
Copyright License Agreement 61030-Copyright license agreement.pdf
Peer-review Report 61030-Peer-review(s).pdf
Scientific Misconduct Check 61030-Bing-Wang JL-1.jpg
Scientific Misconduct Check 61030-Bing-Fan JR-2.png
Scientific Misconduct Check 61030-Scientific misconduct check.pdf
Scientific Editor Work List 61030-Scientific editor work list.pdf