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3/30/2021 7:06:58 AM | Browse: 47 | Download: 102
Publication Name World Journal of Gastroenterology
Manuscript ID 61335
Country/Territory United States
2020-12-03 16:21
Peer-Review Started
2020-12-03 16:21
To Make the First Decision
Return for Revision
2020-12-21 05:03
2021-01-04 19:39
Second Decision
2021-01-30 14:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-02-01 22:28
Articles in Press
2021-02-01 22:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-02-26 00:20
Publish the Manuscript Online
2021-03-30 07:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Non-responsive celiac disease in children on a gluten free diet
Manuscript Source Unsolicited Manuscript
All Author List Gopal Veeraraghavan, Amelie Therrien, Maya Degroote, Allison McKeown, Paul D Mitchell, Jocelyn A Silvester, Daniel A Leffler, Alan M Leichtner, Ciaran P Kelly and Dascha C Weir
Funding Agency and Grant Number
Funding Agency Grant Number
Boston Children's Hospital and the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health P30DK034854
Boston Children's Hospital and the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health K23DK119584
Boston Children's Hospital and the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health T32DK07760
DG Kinnear Award from the Association Quebecoise des Gastroenterologues du Quebec
Phase 2 Award from the Fonds de Recherche Sante Quebec
Corresponding Author Dascha C Weir, MD, N/A, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, United States. dascha.weir@childrens.harvard.edu
Key Words Celiac disease; Non-responsive celiac disease; Children; Gluten-free diet; Constipation; Abdominal pain
Core Tip This is a retrospective chart review study of children < 18 years of age diagnosed with celiac disease (CeD) by positive serology and biopsies showing Marsh III histology to characterize non-responsive CeD (NRCD). NRCD was attributed to a wide variety of diagnoses with gluten exposure (30%) and constipation (20%) being the most common causes. Most (64%) patients improved on follow-up. Our study highlights the importance of performing a diligent search for etiologies of NRCD when there are persistent symptoms despite following a gluten-free diet and reinforces the need for close follow up in the first year of the diagnosis of CeD.
Publish Date 2021-03-30 07:03
Citation Veeraraghavan G, Therrien A, Degroote M, McKeown A, Mitchell PD, Silvester JA, Leffler DA, Leichtner AM, Kelly CP, Weir DC. Non-responsive celiac disease in children on a gluten free diet. World J Gastroenterol 2021; 27(13): 1311-1320
URL https://www.wjgnet.com/1007-9327/full/v27/i13/1311.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i13.1311
Full Article (PDF) WJG-27-1311.pdf
Full Article (Word) WJG-27-1311.docx
Manuscript File 61335_Auto_Edited_LM.docx
Answering Reviewers 61335-Answering reviewers.pdf
Audio Core Tip 61335-Audio core tip.mp3
Biostatistics Review Certificate 61335-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61335-Conflict-of-interest statement.pdf
Copyright License Agreement 61335-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 61335-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 61335-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 61335-Institutional review board statement.pdf
Peer-review Report 61335-Peer-review(s).pdf
Scientific Misconduct Check 61335-Scientific misconduct check.pdf
Scientific Editor Work List 61335-Scientific editor work list.pdf