Publication Name	World Journal of Gastroenterology
Manuscript ID	61426
Country	China

Received	2020-12-06 13:00
Peer-Review Started	2020-12-06 13:02
To Make the First Decision
Return for Revision	2020-12-17 20:02
Revised	2020-12-21 11:05
Second Decision	2021-01-07 12:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-01-07 19:12
Articles in Press	2021-01-07 19:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-01-24 08:26
Typeset the Manuscript	2021-02-03 02:21
Publish the Manuscript Online	2021-02-05 10:20

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis
Manuscript Source	Unsolicited Manuscript
All Author List	Peng Deng, Ming Sun, Wen-Yan Zhao, Bin Hou, Kai Li, Tao Zhang and Feng Gu
Funding Agency and Grant Number
Corresponding Author	Feng Gu, PhD, Chief Physician, Department of Ophthalmology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North street, Heping District, Shenyang 110001, Liaoning Province, China. fenggu78186069@163.com
Key Words	Gastric cancer; Progression; Chemoresistance; CircVAPA; miR-125b-5p; STAT3
Core Tip	We concluded that circVAPA contributed to chemotherapy resistance and malignant progression of gastric cancer (GC) by miR-125b-5p/STAT3 signaling. Our findings present novel insights into the mechanism that circVAPA regulates chemotherapy resistance of GC. CircVAPA and miR-125b-5p may be considered as potential targets for GC therapy.
Publish Date	2021-02-05 10:20
Citation	Deng P, Sun M, Zhao WY, Hou B, Li K, Zhang T, Gu F. Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis. World J Gastroenterol 2021; 27(6): 487-500
URL	https://www.wjgnet.com/1007-9327/full/v27/i6/487.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i6.487

Full Article (PDF)	WJG-27-487.pdf
Full Article (Word)	WJG-27-487.docx
Manuscript File	61426_Auto_Edited_WangTQ.docx
Answering Reviewers	61426-Answering reviewers.pdf
Audio Core Tip	61426-Audio core tip.mp3
Biostatistics Review Certificate	61426-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	61426-Conflict-of-interest statement.pdf
Copyright License Agreement	61426-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	61426-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	61426-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	61426-Language certificate.pdf
Peer-review Report	61426-Peer-review(s).pdf
Scientific Misconduct Check	61426-Bing-Gong ZM-1.png
Scientific Misconduct Check	61426-Bing-Fan JR-2.png
Scientific Misconduct Check	61426-Scientific misconduct check.pdf
Scientific Editor Work List	61426-Scientific editor work list.pdf