Publication Name	World Journal of Gastroenterology
Manuscript ID	62980
Country	China

Received	2021-01-24 16:27
Peer-Review Started	2021-01-24 16:32
To Make the First Decision
Return for Revision	2021-03-07 04:19
Revised	2021-03-24 07:30
Second Decision	2021-04-19 12:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-04-22 03:47
Articles in Press	2021-04-22 03:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-05 10:57
Typeset the Manuscript	2021-05-31 11:19
Publish the Manuscript Online	2021-06-08 10:51

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Advances of liver injury in COVID-19: Detection, pathogenesis and treatment
Manuscript Source	Invited Manuscript
All Author List	Yue Cai, Li-Ping Ye, Ya-Qi Song, Xin-Li Mao, Li Wang, Yan-Zhi Jiang, Wei-Tao Que and Shao-Wei Li
Funding Agency and Grant Number	Funding Agency Grant Number Program of Taizhou Science and Technology Grant 20ywb29 Medical Health Science and Technology Project of Zhejiang Province 2021PY083 Medical Health Science and Technology Project of Zhejiang Province 2019KY239 Key Technology Research and Development Program of Zhejiang Province 2019C03040 Major Research Program of Taizhou Enze Medical Center Grant 19EZZDA2
Corresponding Author	Shao-Wei Li, PhD, Academic Fellow, Assistant Professor, Associate Research Scientist, Instructor, Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, No. 150 Xinmen Street, Linhai 317000, Zhejiang Province, China. li_shaowei81@hotmail.com
Key Words	COVID-19; Liver injury; Clinical features; Potential mechanism; Treatment
Core Tip	Coronavirus disease 2019 (COVID-19) has assumed pandemic proportions, and has resulted in several hundred thousand deaths globally. Although the lung is the main organ that is damaged in COVID-19, approximately 60% of the patients have been reported to develop various degrees of liver injury in several studies. Accumulating clinical data show that liver damage is related to the severity of COVID-19 and is a major cause of death from COVID-19, especially in the presence of hepatic failure. The exact cause of liver injury in patients with COVID-19 remains unclear and the specific underlying mechanism(s) need to be elucidated.
Publish Date	2021-06-08 10:51
Citation	Cai Y, Ye LP, Song YQ, Mao XL, Wang L, Jiang YZ, Que WT, Li SW. Advances of liver injury in COVID-19: Detection, pathogenesis and treatment. World J Gastroenterol 2021; 27(22): 3022-3036
URL	https://www.wjgnet.com/1007-9327/full/v27/i22/3022.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i22.3022

Full Article (PDF)	WJG-27-3022.pdf
Full Article (Word)	WJG-27-3022.docx
Manuscript File	62980_Auto_Edited_LM_WangTQ.docx
Answering Reviewers	62980-Answering reviewers.pdf
Audio Core Tip	62980-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	62980-Conflict-of-interest statement.pdf
Copyright License Agreement	62980-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	62980-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	62980-Language certificate.pdf
Peer-review Report	62980-Peer-review(s).pdf
Scientific Misconduct Check	62980-Bing-Liu M-1.png
Scientific Misconduct Check	62980-Scientific misconduct check.pdf
Scientific Editor Work List	62980-Scientific editor work list.pdf
CrossCheck Report	62980-CrossCheck report.pdf