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7/19/2021 2:13:13 PM | Browse: 33 | Download: 35
Publication Name World Journal of Gastroenterology
Manuscript ID 63132
Country/Territory China
Received
2021-01-31 11:49
Peer-Review Started
2021-01-31 11:59
To Make the First Decision
Return for Revision
2021-05-13 01:03
Revised
2021-05-15 09:02
Second Decision
2021-06-22 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-06-22 10:00
Articles in Press
2021-06-22 10:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-25 20:46
Typeset the Manuscript
2021-07-15 08:18
Publish the Manuscript Online
2021-07-19 14:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Minireviews
Article Title Dysregulated liver function in SARS-CoV-2 infection: Current understanding and perspectives
Manuscript Source Invited Manuscript
All Author List Yi-Ke Huang, Yu-Jia Li, Bin Li, Pan Wang and Qing-Hua Wang
Funding Agency and Grant Number
Funding Agency Grant Number
Sino-German Center for Research Promotion, National Natural Science Foundation of China C-0029
Health Commission of Chengdu 2020179
Corresponding Author Qing-Hua Wang, MD, Chief Doctor, Department of Emergency, the Traditional Chinese Medicine Hospital of Wenjiang District, No. 156 Dongda Street, Chengdu 611130, Sichuan Province, China. qinghuawang2015@126.com
Key Words SARS-CoV-2; COVID-19; Dysregulated liver function; Cytokine storm
Core Tip The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is one of the most influential emerging infectious diseases worldwide. Accumulating evidence suggests that liver injury is pretty common in COVID-19 patients and many severe cases tend to be associated with dysregulated liver functions. Here in this review, we summarize the currently available data of liver enzyme abnormalities in confirmed patients with COVID-19 and analyze multiple risk factors for liver injury. However, the mechanism of liver impairment seems to be multifactorial. The evidence of direct liver injury triggered by SARS-CoV-2 infection or indirect liver injury induced by overwhelmed cytokine storm will also be discussed.
Publish Date 2021-07-19 14:10
Citation Huang YK, Li YJ, Li B, Wang P, Wang QH. Dysregulated liver function in SARS-CoV-2 infection: Current understanding and perspectives. World J Gastroenterol 2021; 27(27): 4358-4370
URL https://www.wjgnet.com/1007-9327/full/v27/i27/4358.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i27.4358
Full Article (PDF) WJG-27-4358.pdf
Full Article (Word) WJG-27-4358.docx
Manuscript File 63132-Review-Filipodia-CL.docx
Answering Reviewers 63132-Answering reviewers.pdf
Audio Core Tip 63132-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 63132-Conflict-of-interest statement.pdf
Copyright License Agreement 63132-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 63132-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 63132-Language certificate.pdf
Peer-review Report 63132-Peer-review(s).pdf
Scientific Misconduct Check 63132-Scientific misconduct check.pdf
Scientific Editor Work List 63132-Scientific editor work list.pdf