Publication Name	World Journal of Methodology
Manuscript ID	63777
Country	Greece

Received	2021-02-04 17:02
Peer-Review Started	2021-02-04 17:02
To Make the First Decision
Return for Revision	2021-06-07 02:38
Revised	2021-06-10 11:54
Second Decision	2021-07-13 03:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-07-13 08:29
Articles in Press	2021-07-13 08:29
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-21 06:22
Typeset the Manuscript	2021-09-11 02:48
Publish the Manuscript Online	2021-09-14 13:45

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Review
Article Title	IgY technology: Methods of developing and evaluating avian immunoglobulins for the in vitro detection of biomolecules
Manuscript Source	Invited Manuscript
All Author List	Chrysoula-Evangelia Karachaliou, Vyronia Vassilakopoulou and Evangelia Livaniou
Funding Agency and Grant Number
Corresponding Author	Evangelia Livaniou, PhD, Academic Research, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research “Demokritos” , IAgia Paraskevi, Athens 15310, Greece. livanlts@rrp.demokritos.gr
Key Words	Animal welfare; Polyclonal IgYs; Egg yolk; IgY technology; Relevant-to-IgY-technology approaches; In vitro immunodetection techniques
Core Tip	IgY technology has been widely used during the last decades, especially as a means for the efficient in vitro immunodetection of biomolecules in various fields of research and disease diagnosis. Despite the very promising relevant new approaches, there is still space for further exploiting the original IgY technology, due to functional, practical and ethical reasons/advantages associated with the unique features of IgYs, the highly efficient isolation of large amounts of IgYs from the immune egg yolk, and the avoidance of animal bleeding, respectively.
Publish Date	2021-09-14 13:45
Citation	Karachaliou CE, Vassilakopoulou V, Livaniou E. IgY technology: Methods of developing and evaluating avian immunoglobulins for the in vitro detection of biomolecules. World J Methodol 2021; 11(5): 243-262
URL	https://www.wjgnet.com/2222-0682/full/v11/i5/243.htm
DOI	https://dx.doi.org/10.5662/wjm.v11.i5.243

Full Article (PDF)	WJM-11-243.pdf
Full Article (Word)	WJM-11-243.docx
Manuscript File	63777-Review-Filipodia.docx
Answering Reviewers	63777-Answering reviewers.pdf
Audio Core Tip	63777-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	63777-Conflict-of-interest statement.pdf
Copyright License Agreement	63777-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	63777-Language certificate.pdf
Peer-review Report	63777-Peer-review(s).pdf
Scientific Misconduct Check	63777-Scientific misconduct check.pdf
Scientific Editor Work List	63777-Scientific editor work list.pdf
CrossCheck Report	63777-CrossCheck report.pdf