Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	64048
Country	Bulgaria

Received	2021-02-07 21:05
Peer-Review Started	2021-02-07 21:29
To Make the First Decision
Return for Revision	2021-03-16 17:18
Revised	2021-03-30 13:17
Second Decision	2021-06-16 13:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-06-16 13:58
Articles in Press	2021-06-16 13:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-29 19:15
Typeset the Manuscript	2021-08-17 13:38
Publish the Manuscript Online	2021-08-20 10:31

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Minireviews
Article Title	Surgical complications in COVID-19 patients in the settings of moderate to severe disease
Manuscript Source	Invited Manuscript
All Author List	Milena Gulinac, Ivan P Novakov, Svetozar Antovic and Tsvetelina Velikova
Funding Agency and Grant Number
Corresponding Author	Tsvetelina Velikova, MD, PhD, Assistant Professor, Department of Clinical Immunology, University Hospital Lozenetz, Kozyak 1 Street, Sofia 1407, Bulgaria. tsvelikova@medfac.mu-sofia.bg
Key Words	COVID-19; SARS-CoV-2; Surgery; Surgery complications; Mortality rate; Acute respiratory distress syndrome; Thrombosis
Core Tip	The clinical outcomes of coronavirus disease-2019 (COVID-19) patients undergoing urgent or emergent surgeries showed that the estimated mean duration of hospitalization was 10.55 d, with 15% admission to the intensive care unit in the postoperative period-up to 15%. Several complications in patients with COVID-19 who underwent surgical procedures were described: Acute respiratory distress syndrome and other pulmonary complications leading to respiratory failure (such as pneumonia, short of breath, dyspnea, fever, cough), cardiovascular system failure (i.e, cardiac arrest, arrhythmia, and infarction), secondary infection, fatigue or myalgia, severe lymphopenia, sepsis/shock, and acute kidney injury, etc. Pulmonary complications were responsible for low survival rate and prolonged immobility in surgical COVID-19 patients, as well as associated with high postoperative mortality (contributing to a 30-d mortality rate of 38%. Furthermore, cancer patients were more likely to contract COVID-19 than non-cancer patients. They were more vulnerable to complications and had a higher mortality postoperative rate. The impact on surgical patients in terms of delay or complications is noteworthy, and it is expected to last further than the end of the pandemic.
Publish Date	2021-08-20 10:31
Citation	Gulinac M, Novakov IP, Antovic S, Velikova T. Surgical complications in COVID-19 patients in the settings of moderate to severe disease. World J Gastrointest Surg 2021; 13(8): 788-795
URL	https://www.wjgnet.com/1948-9366/full/v13/i8/788.htm
DOI	https://dx.doi.org/10.4240/wjgs.v13.i8.788

Full Article (PDF)	WJGS-13-788.pdf
Full Article (Word)	WJGS-13-788.docx
Manuscript File	64048-Review-FilipodiaCL.docx
Answering Reviewers	64048-Answering reviewers.pdf
Audio Core Tip	64048-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64048-Conflict-of-interest statement.pdf
Copyright License Agreement	64048-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	64048-Language certificate.pdf
Peer-review Report	64048-Peer-review(s).pdf
Scientific Misconduct Check	64048-Scientific misconduct check.pdf
Scientific Editor Work List	64048-Scientific editor work list.pdf
CrossCheck Report	64048-CrossCheck report.pdf