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9/15/2021 10:42:57 AM | Browse: 389 | Download: 733
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Received |
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2021-03-17 13:54 |
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Peer-Review Started |
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2021-03-17 13:59 |
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To Make the First Decision |
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Return for Revision |
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2021-04-16 01:34 |
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Revised |
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2021-04-27 15:34 |
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Second Decision |
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2021-08-30 03:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-30 09:15 |
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Articles in Press |
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2021-08-30 09:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-09-13 00:44 |
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Publish the Manuscript Online |
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2021-09-15 10:33 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Editorial |
Article Title |
Induced pluripotent stem cells as an innovative model to study drug induced pancreatitis
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Manuscript Source |
Invited Manuscript |
All Author List |
Elena Genova, Gabriele Stocco and Giuliana Decorti |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Italian Ministry of Health (IRCCS Burlo Garofolo) |
RC 7_2014 |
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Corresponding Author |
Giuliana Decorti, MD, Full Professor, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65, Trieste 34137, Italy. decorti@units.it |
Key Words |
nduced pluripotent stem cells; Therapy personalization; Patient-specific cells; Drug-induced pancreatitis; Thiopurines; Inflammatory bowel disease |
Core Tip |
About 5% of inflammatory bowel disease patients develop pancreatitis after thiopurine administration. The mechanism of this adverse effect is still not clear making it difficult to prevent. By differentiating induced pluripotent stem cells into their pancreatic exocrine counterpart, it is possible to set up innovative personalized in vitro models to study this adverse effect in a more effective way. |
Publish Date |
2021-09-15 10:33 |
Citation |
Genova E, Stocco G, Decorti G. Induced pluripotent stem cells as an innovative model to study drug induced pancreatitis. World J Gastroenterol 2021; 27(35): 5796-5802 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i35/5796.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i35.5796 |
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