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9/26/2021 6:51:49 AM | Browse: 61 | Download: 104
Publication Name World Journal of Nephrology
Manuscript ID 66103
Country/Territory Japan
Received
2021-03-21 03:52
Peer-Review Started
2021-03-21 03:55
To Make the First Decision
Return for Revision
2021-05-06 02:20
Revised
2021-05-15 01:14
Second Decision
2021-08-10 03:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-10 07:08
Articles in Press
2021-08-10 07:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-09-21 12:15
Publish the Manuscript Online
2021-09-26 03:15
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Minireviews
Article Title Trends in pediatric nephrotic syndrome
Manuscript Source Invited Manuscript
All Author List Hiroshi Tamura
Funding Agency and Grant Number
Corresponding Author Hiroshi Tamura, MD, PhD, Assistant Professor, Department of Pediatrics, Kumamoto University, 1-1-1 Honjo, Chuo-ku, kumamoto 8608556, Japan. bohm1905ht@kuh.kumamoto-u.ac.jp
Key Words Nephrotic syndrome; Gene; Immunity; Viral infection; Children
Core Tip There is no doubt that some vascular hyperpermeability factor is involved in the incidence of proteinuria in idiopathic nephrotic syndrome (INS). However, no etiological molecule has been identified in INS as a factor for increasing the permeability of renal glomerular capillaries with reproducibility and clinical consistency. In addition, since the onset is sometimes observed in the family, there is high incidence of INS in East Asian children and there is the association of steroid-sensitive NS in childhood in Japan with the HLA-DR/DQ region, it is highly possible that some genetic factors are involved in the onset of NS. In our opinion, INS is a multifactorial disease in which immunological stimuli, trigger the production of substances that impair podocytes, resulting in dysfunction of the slit membrane and cause proteinuria.
Publish Date 2021-09-26 03:15
Citation Tamura H. Trends in pediatric nephrotic syndrome. World J Nephrol 2021; 10(5): 88-100
URL https://www.wjgnet.com/2220-6124/full/v10/i5/88.htm
DOI https://dx.doi.org/10.5527/wjn.v10.i5.88
Full Article (PDF) WJN-10-88.pdf
Full Article (Word) WJN-10-88.docx
Manuscript File 66103_Auto_Edited-JPY.docx
Answering Reviewers 66103-Answering reviewers.pdf
Audio Core Tip 66103-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 66103-Conflict-of-interest statement.pdf
Copyright License Agreement 66103-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 66103-Language certificate.pdf
Peer-review Report 66103-Peer-review(s).pdf
Scientific Misconduct Check 66103-Bing-Fan JR-2.png
Scientific Misconduct Check 66103-Scientific misconduct check.pdf
Scientific Editor Work List 66103-Scientific editor work list.pdf