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1/11/2022 9:08:44 AM | Browse: 217 | Download: 566
Publication Name World Journal of Gastroenterology
Manuscript ID 67670
Country/Territory Sudan
Received
2021-04-29 01:02
Peer-Review Started
2021-04-29 01:04
To Make the First Decision
Return for Revision
2021-06-17 02:28
Revised
2021-07-13 07:05
Second Decision
2021-12-31 03:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-31 21:58
Articles in Press
2021-12-31 21:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-12-13 22:21
Typeset the Manuscript
2022-01-05 07:27
Publish the Manuscript Online
2022-01-11 08:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Observational Study
Article Title Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach
Manuscript Source Invited Manuscript
All Author List Abeer Babiker Idris, Alaa B Idris, Manal A Gumaa, Mohammed Babiker Idris, Amanda Elgoraish, Mohamed Mansour, Dalia Allam, Bashir MO Arbab, Nazar Beirag, El-Amin M Ibrahim and Mohamed A Hassan
Funding Agency and Grant Number
Corresponding Author Abeer Babiker Idris, DSc, Academic Research, Department of Agricultural Science and Technology, Institute of Natural and Applied Sciences, Erciyes University, Merkez Kampüs Talas Yolu Melikgazi, Kayseri 38039, Türkiye. abeer.babiker89@gmail.com
Key Words 5’-region; Promoter; TNF-A; Helicobacter pylori; In silico analysis; Sudan
Core Tip According to the literature, a considerable number of polymorphisms have been discovered in the tumor necrosis factor-alpha (TNF-A) promoter. A crucial question is whether these polymorphisms have any significant functional impact on disease incidence or severity. Seven single nucleotide polymorphisms were detected in the TNF-A 5’-region; only one of them, TNF-A-76, was located at the in silico-predicted promoter region (-146 to +10). This single nucleotide polymorphism may lead to the modification of the transcriptional regulation of TNF-A in Helicobacter pylori infection. Nevertheless, this conclusion cannot substitute for the experimental proofs, but it can provide direction or insight for them.
Publish Date 2022-01-11 08:34
Citation Idris AB, Idris AB, Gumaa MA, Idris MB, Elgoraish A, Mansour M, Allam D, Arbab BM, Beirag N, Ibrahim EAM, Hassan MA. Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach. World J Gastroenterol 2022; 28(2): 242-262
URL https://www.wjgnet.com/1007-9327/full/v28/i2/242.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i2.242
Full Article (PDF) WJG-28-242.pdf
Full Article (Word) WJG-28-242.docx
STROBE Statement 67670-STROBE-Statement-revision.pdf
Manuscript File 67670_Auto_Edited-ML-FilipodiaCL.docx
Answering Reviewers 67670-Answering reviewers.pdf
Audio Core Tip 67670-Audio core tip.m4a
Biostatistics Review Certificate 67670-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67670-Conflict-of-interest statement.pdf
Copyright License Agreement 67670-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 67670-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 67670-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67670-Language certificate.pdf
Peer-review Report 67670-Peer-review(s).pdf
Scientific Misconduct Check 67670-Bing-Liu M-1.png
Scientific Misconduct Check 67670-Bing-Liu M-2.png
Scientific Editor Work List 67670-Scientific editor work list.pdf